Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2844425 | 0.79 | MCHR1 (0.41) | CNR2KDM4EMEN1KMT2AHIF1A | |
| SCHEMBL2841256 | 0.77 | ALDH1A1 (0.44) | KDM4EMEN1KMT2ALMNAMAPT | |
| SCHEMBL2839900 | 0.76 | GABRA1 (0.45) | CNR1CNR2LMNAMAPTCYP3A4 | |
| SCHEMBL2849926 | 0.75 | CYP1A2 (0.46) | CNR1CNR2KDM4EMEN1KMT2A | |
| SCHEMBL2842248 | 0.75 | L3MBTL1 (0.41) | KDM4EMAPTALDH1A1GABRA1GABRB2 | |
| SCHEMBL2844525 | 0.74 | HPGD (0.43) | KDM4EMEN1KMT2ALMNAMAPT | |
| SCHEMBL7169652 | 0.72 | TSHR (0.45) | KDM4EMEN1KMT2ALMNACYP3A4 | |
| SCHEMBL2839258 | 0.72 | CYP1A2 (0.49) | CNR1CNR2KDM4EMEN1KMT2A | |
| SCHEMBL2848364 | 0.70 | MCHR1 (0.42) | KDM4ELMNAMAPTHTR2BALDH1A1 | |
| SCHEMBL2423123 | 0.70 | HTT (0.49) | KDM4EMEN1KMT2ACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |