Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30589330 | 0.81 | PGR (0.44) | PGR | |
| SCHEMBL21061462 | 0.81 | PGR (0.44) | PGR | |
| SCHEMBL61843 | 0.80 | PGR (0.56) | PGR | |
| SCHEMBL1223242 | 0.78 | PGR (0.55) | PGR | |
| SCHEMBL31606006 | 0.77 | PGR (0.41) | PGR | |
| SCHEMBL4110085 | 0.75 | PGR (1.00) | PGR | |
| SCHEMBL5499005 | 0.75 | PGR (0.55) | PGR | |
| SCHEMBL4215455 | 0.72 | PGR (1.00) | PGR | |
| SCHEMBL4101026 | 0.71 | PGR (1.00) | PGR | |
| SCHEMBL12306672 | 0.71 | KCNK2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130012702-A1 | PURIFICATION OF PROGESTERONE RECEPTOR MODULATORS | WYETH LLC (US) | 2013-01-10 | — | — | US | disclosed |
| US-20130012702-A1 | PURIFICATION OF PROGESTERONE RECEPTOR MODULATORS | WYETH LLC (US) | 2013-01-10 | — | — | US | disclosed |
| US-8309594-B2 | Purification of progesterone receptor modulators | WYETH LLC (US) | 2012-11-13 | — | — | US | disclosed |
| US-8309594-B2 | Purification of progesterone receptor modulators | WYETH LLC (US) | 2012-11-13 | — | — | US | disclosed |
| US-8129523-B2 | Coupling process for generating reactive boron-containing derivatives of N-substituted pyrrole-2-carbonitriles to produce biaryls | WYETH LLC (US) | 2012-03-06 | — | — | US | disclosed |
| US-8129523-B2 | Coupling process for generating reactive boron-containing derivatives of N-substituted pyrrole-2-carbonitriles to produce biaryls | WYETH LLC (US) | 2012-03-06 | — | — | US | disclosed |
| US-20110178311-A1 | Purification of Progesterone Receptor Modulators | WYETH LLC (US) | 2011-07-21 | — | — | US | disclosed |
| US-20110178311-A1 | Purification of Progesterone Receptor Modulators | WYETH LLC (US) | 2011-07-21 | — | — | US | disclosed |
| US-20090143577-A1 | PURIFICATION OF PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2009-06-04 | — | — | US | disclosed |
| US-20090143577-A1 | PURIFICATION OF PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2009-06-04 | — | — | US | disclosed |
| US-7514466-B2 | Purification of progesterone receptor modulators | WYETH (US) | 2009-04-07 | — | — | US | disclosed |
| US-7514466-B2 | Purification of progesterone receptor modulators | WYETH (US) | 2009-04-07 | — | — | US | disclosed |
| US-20090054663-A1 | COUPLING PROCESS FOR GENERATING REACTIVE BORON-CONTAINING DERIVATIVES OF N-SUBSTITUTED PYRROLE-2-CARBONITRILES TO PRODUCE BIARYLS | WYETH (US) | 2009-02-26 | — | — | US | disclosed |
| US-20090054663-A1 | COUPLING PROCESS FOR GENERATING REACTIVE BORON-CONTAINING DERIVATIVES OF N-SUBSTITUTED PYRROLE-2-CARBONITRILES TO PRODUCE BIARYLS | WYETH (US) | 2009-02-26 | — | — | US | disclosed |
| US-7446211-B2 | Reacting 1-methylpyrrole-2-carbonitrile with triisopropylborate in presence of lithium diisopropyl amine to produce (5-cyano-1-methyl-1H-pyrrol-2-yl) boronic acid | WYETH (US) | 2008-11-04 | — | — | US | disclosed |
| US-7446211-B2 | Reacting 1-methylpyrrole-2-carbonitrile with triisopropylborate in presence of lithium diisopropyl amine to produce (5-cyano-1-methyl-1H-pyrrol-2-yl) boronic acid | WYETH (US) | 2008-11-04 | — | — | US | disclosed |
| US-20070213526-A1 | Purification of progesterone receptor modulators | WYETH (US) | 2007-09-13 | — | — | US | disclosed |
| US-20070213526-A1 | Purification of progesterone receptor modulators | WYETH (US) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054663-A1 | COUPLING PROCESS FOR GENERATING REACTIVE BORON-CONTAINING DERIVATIVES OF N-SUBSTITUTED PYRROLE-2-CARBONITRILES TO PRODUCE BIARYLS | BOLA2; BOLA2B, BRI3BP, BROX | PGR 1401/4885 |
| US-20130012702-A1 | PURIFICATION OF PROGESTERONE RECEPTOR MODULATORS | PGR, PGRMC1, GNRHR | PGR 1/4885 |
| US-20070213526-A1 | Purification of progesterone receptor modulators | PGR, PGRMC1, PGRMC2 | PGR 1/4885 |
| US-20090143577-A1 | PURIFICATION OF PROGESTERONE RECEPTOR MODULATORS | PGR, PGRMC1, GNRHR | PGR 1/4885 |
| US-20110178311-A1 | Purification of Progesterone Receptor Modulators | PGR, PGRMC1, PGRMC2 | PGR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.