Carbon Monoxide

Carbon Monoxide

SCHEMBL7170133

C1CCC(P(C2CCCCC2)C2CCCCC2)CC1.C1CCC(P(C2CCCCC2)C2CCCCC2)CC1.[C]=O.[Ru]C=Cc1ccccc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MAPK1 P28482 1/20 0.41
TRPM8 Q7Z2W7 2/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 2/20 0.35
RAB9A P51151 1/20 0.35
ALDH1A1 P00352 1/20 0.34
FBP1 P09467 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4248410 0.93 HSP90AA1 (0.40) HSP90AA1SMN1; SMN2MAPK1TRPM8KDM4E
Carbon Monoxide SCHEMBL8744054 0.80 HSP90AA1 (0.38) HSP90AA1SMN1; SMN2MAPK1TRPM8KDM4E
SCHEMBL3276196 0.78 GAA (0.38) HSP90AA1SMN1; SMN2MAPK1TRPM8KDM4E
SCHEMBL2868301 0.78 GAA (0.38) HSP90AA1SMN1; SMN2MAPK1TRPM8KDM4E
Carbon Monoxide SCHEMBL6743820 0.77 KDM1A (0.37) HSP90AA1SMN1; SMN2MAPK1TRPM8ALDH1A1
Hydrochloric Acid SCHEMBL3337845 0.76 GAA (0.37) HSP90AA1SMN1; SMN2MAPK1TRPM8KDM4E
Hydrochloric Acid SCHEMBL4542347 0.76 GAA (0.37) HSP90AA1SMN1; SMN2MAPK1TRPM8KDM4E
SCHEMBL6568409 0.75 GAA (0.39) HSP90AA1SMN1; SMN2MAPK1TRPM8KDM4E
Hydrochloric Acid SCHEMBL175377 0.73 POLB (0.37) HSP90AA1SMN1; SMN2MAPK1TRPM8KDM4E
Bromide SCHEMBL2467102 0.73 POLB (0.37) HSP90AA1SMN1; SMN2MAPK1TRPM8KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6566457-B2 Graft polymers BASF AKTIENGESELLSCHAFT (DE) 2003-05-20 US disclosed
US-20020004565-A1 Novel impact modifiers prepared from (partially) hydrogenated butadiene-containing dispersions BASF AKTIENGESELLSCHAFT (DE) 2002-01-10 US disclosed
EP-1148073-A1 Impact strength modifier based on dispersions containing hydrogenated or partially hydrogenated butadiene BASF AKTIENGESELLSCHAFT (DE) 2001-10-24 EP disclosed