Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 12/20 | 0.36 |
| ▸ | NPY1R | P25929 | 7/20 | 0.36 |
| ▸ | NPY2R | P49146 | 5/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7170068 | 0.81 | NPY4R (0.35) | NPY4RNPY1RNPY2RNPY5RNOS1 | |
| SCHEMBL7166055 | 0.81 | ANPEP (0.36) | NPY4RNPY1RNPY2RNPY5RNOS1 | |
| SCHEMBL11304461 | 0.79 | OTC (0.38) | NPY4RNPY1RNPY2RNPY5RNOS1 | |
| SCHEMBL7904179 | 0.76 | NOS1 (0.41) | NPY4RNOS1NOS3NOS2 | |
| SCHEMBL7170368 | 0.74 | NPY4R (0.42) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL3308394 | 0.74 | NPY4R (0.38) | NPY4RNPY1RNPY2RNPY5RANPEP | |
| SCHEMBL4961940 | 0.72 | MEN1 (0.35) | — | |
| SCHEMBL8740426 | 0.72 | MEN1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL11137955 | 0.72 | NPY4R (0.37) | NPY4RNPY1RNPY2RNPY5RANPEP | |
| SCHEMBL7357498 | 0.71 | ACHE (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789578-B1 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON INC (US) | 2003-06-04 | — | — | EP | disclosed |
| EP-0789578-A4 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON INC (US) | 2000-09-20 | — | — | EP | disclosed |
| EP-0789578-A1 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1997-08-20 | — | — | EP | disclosed |
| US-5550262-A | TREATMENT OF MUSCLES WASTING DISEASES | CEPHALON, INC. (US) | 1996-08-27 | — | — | US | disclosed |
| WO-1996014857-A1 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1996-05-23 | — | — | WO | disclosed |