Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.63 |
| ▸ | CRHBP | P24387 | 1/20 | 0.61 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.56 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.56 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10013442 | 0.91 | MEN1 (0.60) | ERBB2HSP90AA1HSP90AB1CRHBPCRHR2 | |
| SCHEMBL10013441 | 0.84 | MEN1 (0.60) | CRHBPCRHR2GAAALDH1A1MEN1 | |
| SCHEMBL3262497 | 0.83 | ERBB2 (0.71) | ERBB2HSP90AA1HSP90AB1GAAHSD17B10 | |
| SCHEMBL11027219 | 0.83 | ERBB2 (0.71) | ERBB2HSP90AA1HSP90AB1CRHBPCRHR2 | |
| SCHEMBL3781935 | 0.82 | CRHBP (0.62) | ERBB2HSP90AA1HSP90AB1CRHBPCRHR2 | |
| SCHEMBL8307085 | 0.82 | CRHBP (0.62) | ERBB2HSP90AA1HSP90AB1CRHBPCRHR2 | |
| SCHEMBL15121247 | 0.81 | HSD17B2 (0.64) | ALDH1A1MEN1KMT2A | |
| SCHEMBL11498348 | 0.81 | CYTH2 (0.55) | ERBB2HSP90AA1HSP90AB1GAAHSD17B10 | |
| SCHEMBL22315132 | 0.81 | MEN1 (0.67) | ERBB2HSP90AA1HSP90AB1CRHBPCRHR2 | |
| SCHEMBL2073110 | 0.81 | CRHBP (0.61) | ERBB2HSP90AA1HSP90AB1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579829-B2 | Aromatic sulfonamide compound | MITSUI CHEMICALS, INC. (JP) | 2003-06-17 | — | — | US | disclosed |
| EP-1138517-A2 | Developer composition and heat sensitive recording material | Mitsui Chemicals, Inc. (JP) | 2001-10-04 | — | — | EP | disclosed |