Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PAM | P19021 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031181 | 0.94 | DGKA (0.41) | DGKA | |
| SCHEMBL28504652 | 0.91 | MAPT (0.41) | MAPTLMNADNM1KDM4EDUSP3 | |
| SCHEMBL28395367 | 0.91 | MAPT (0.41) | MAPTLMNADNM1KDM4EDUSP3 | |
| Sulfuric Acid SCHEMBL29140986 | 0.90 | MAPT (0.44) | MAPTLMNADNM1KDM4EDUSP3 | |
| SCHEMBL6857401 | 0.86 | DNM1 (0.39) | MAPTLMNADNM1KDM4EDUSP3 | |
| Hydrochloric Acid SCHEMBL7213491 | 0.86 | MAPT (0.47) | MAPTLMNADNM1KDM4EDUSP3 | |
| SCHEMBL7171799 | 0.81 | DNM1 (0.38) | MAPTLMNADNM1KDM4EDUSP3 | |
| Sulfuric Acid SCHEMBL29112174 | 0.75 | DNM1 (0.45) | MAPTLMNADNM1KDM4EDUSP3 | |
| SCHEMBL28608284 | 0.74 | FAAH (0.38) | MAPTLMNAMEN1KMT2ACA12 | |
| SCHEMBL29005882 | 0.74 | FAAH (0.38) | MAPTLMNAMEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569414-B1 | Panthenol and nicotinic acid amide; lipid-soluble ester alcohol or ester polyol by reacting an epoxy fatty acid ester with a mono- or polyhydric alcohol | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-05-27 | — | — | US | disclosed |