Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7171975 | 1.00 | ALDH1A1 (0.42) | ALDH1A1NPSR1CYP2C19L3MBTL1CYP2C9 | |
| SCHEMBL28564892 | 0.88 | ALDH1A1 (0.41) | ALDH1A1NPSR1CYP2C19L3MBTL1CYP2C9 | |
| SCHEMBL16693277 | 0.87 | PTGES (0.42) | ALDH1A1NPSR1CYP2C19L3MBTL1CYP2C9 | |
| SCHEMBL373839 | 0.84 | ALDH1A1 (0.41) | ALDH1A1NPSR1CYP2C19L3MBTL1CYP2C9 | |
| SCHEMBL7174763 | 0.84 | ALDH1A1 (0.41) | ALDH1A1NPSR1CYP2C19L3MBTL1CYP2C9 | |
| SCHEMBL8855913 | 0.82 | ALDH1A1 (0.39) | ALDH1A1NPSR1CYP2C19L3MBTL1CYP2C9 | |
| SCHEMBL7174796 | 0.82 | ALDH1A1 (0.39) | ALDH1A1NPSR1CYP2C19L3MBTL1CYP2C9 | |
| SCHEMBL6545886 | 0.80 | HCAR2 (0.49) | ALDH1A1L3MBTL1PPARGMAPTKMT2A | |
| SCHEMBL6545884 | 0.80 | HCAR2 (0.49) | ALDH1A1L3MBTL1PPARGMAPTKMT2A | |
| SCHEMBL28553086 | 0.79 | MEN1 (0.41) | ALDH1A1NPSR1L3MBTL1PPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722110-B1 | Water absorptive soft contact lens | MENICON CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-5661194-A | POLYMER FROM MONOMERS OF (METH)ACRYLAMIDE TYPE MONOMER, FLUOROALKYL (SILICON-CONTAINING ALKYL) FUMARATE MONOMER, AND CROSSLINKING MONOMER | MENICON CO., LTD. (JP) | 1997-08-26 | — | — | US | disclosed |
| EP-0722110-A2 | Water absorptive soft contact lens | Menicon Co., Ltd. (JP) | 1996-07-17 | — | — | EP | disclosed |