SCHEMBL28564892

SCHEMBL28564892

CC=CC(=O)OCc1ccc(N=Nc2c(O)ccc(C(=O)c3ccccc3)c2O)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
NPSR1 Q6W5P4 3/20 0.41
CYP2C19 P33261 3/20 0.41
CYP2C9 P11712 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 1/20 0.41
AKR1B10 O60218 2/20 0.40
AKR1B1 P15121 2/20 0.40
TTR P02766 1/20 0.40
CA12 O43570 2/20 0.39
CA4 P22748 2/20 0.39
CA6 P23280 2/20 0.39
CA5A P35218 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA14 Q9ULX7 2/20 0.39
CA5B Q9Y2D0 2/20 0.39
HCAR2 Q8TDS4 1/20 0.39
PPARG P37231 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28552033 0.88 ALOX5 (0.42) ALDH1A1CYP2C19CYP2C9CYP1A2CYP3A4
SCHEMBL7171972 0.88 ALDH1A1 (0.42) ALDH1A1NPSR1CYP2C19CYP2C9L3MBTL1
SCHEMBL7171975 0.88 ALDH1A1 (0.42) ALDH1A1NPSR1CYP2C19CYP2C9L3MBTL1
SCHEMBL28095842 0.85 L3MBTL1 (0.38) ALDH1A1NPSR1CYP2C19L3MBTL1CYP1A2
SCHEMBL373839 0.82 ALDH1A1 (0.41) ALDH1A1NPSR1CYP2C19CYP2C9L3MBTL1
SCHEMBL7174763 0.82 ALDH1A1 (0.41) ALDH1A1NPSR1CYP2C19CYP2C9L3MBTL1
SCHEMBL23406875 0.81 ESRRG (0.36) ALDH1A1NPSR1L3MBTL1PPARGHPGD
SCHEMBL28095795 0.78 AKR1B10 (0.37) ALDH1A1NPSR1AKR1B10AKR1B1HPGD
SCHEMBL23406874 0.77 MAPT (0.33) ALDH1A1NPSR1CYP2C19L3MBTL1CYP1A2
SCHEMBL3185919 0.77 PPARG (0.45) ALDH1A1NPSR1L3MBTL1PPARGHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112703213-A Polymer material 株式会社目立康 2021-04-23 CN disclosed