Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7174038 | 0.84 | TAAR1 (0.39) | MMP1MMP3MMP9MMP2MMP13 | |
| SCHEMBL7172185 | 0.81 | MMP3 (0.55) | PPARGMMP1MMP3MMP9ADAMTS4 | |
| SCHEMBL7172194 | 0.80 | PPARG (0.41) | PPARGS1PR1S1PR3SMN1; SMN2KDM4E | |
| SCHEMBL7172616 | 0.78 | MMP3 (0.46) | PPARGSMN1; SMN2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL7177123 | 0.78 | MMP3 (0.57) | PPARGMMP1MMP3MMP9MMP2 | |
| SCHEMBL7174311 | 0.76 | MMP3 (0.48) | PPARGS1PR1S1PR3MMP1MMP3 | |
| SCHEMBL7172637 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPK1MMP1ACACBMMP3 | |
| SCHEMBL7177453 | 0.76 | MMP3 (0.55) | MMP1MMP3MMP9MMP2 | |
| SCHEMBL7170041 | 0.74 | MMP3 (0.52) | PPARGSMN1; SMN2MMP1MMP3MMP9 | |
| SCHEMBL7170036 | 0.74 | MMP2 (0.57) | MMP1MMP3MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576628-B1 | Matrix metalloprotease inhibitors; arthritis, corneal ulcers, arteriosclerosis | ROCHE DIAGNOSTICS GMBH (DE) | 2003-06-10 | — | — | US | disclosed |