Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7171336 | 0.96 | KMT2A (0.43) | KMT2AADRA2BADRA2AADRA2CALDH1A1 | |
| Hydrochloric Acid SCHEMBL7177034 | 0.96 | KMT2A (0.43) | KMT2AADRA2BADRA2AADRA2CALDH1A1 | |
| Hydrochloric Acid SCHEMBL7175727 | 0.96 | KMT2A (0.43) | KMT2AADRA2BADRA2AADRA2CALDH1A1 | |
| Hydrochloric Acid SCHEMBL7177916 | 0.96 | KMT2A (0.43) | KMT2AADRA2BADRA2AADRA2CALDH1A1 | |
| Hydrochloric Acid SCHEMBL7176630 | 0.96 | KMT2A (0.43) | KMT2AADRA2BADRA2AADRA2CALDH1A1 | |
| Hydrochloric Acid SCHEMBL7180472 | 0.96 | KMT2A (0.43) | KMT2AADRA2BADRA2AADRA2CALDH1A1 | |
| SCHEMBL14082022 | 0.84 | KMT2A (0.41) | KMT2AADRA2BADRA2AADRA2CALDH1A1 | |
| Hydrochloric Acid SCHEMBL7177948 | 0.83 | ALDH1A1 (0.57) | KMT2AALDH1A1POLBLMNATLR8 | |
| SCHEMBL6357965 | 0.81 | TP53 (0.47) | KMT2AALDH1A1POLBMAPTHTR2C | |
| Hydrochloric Acid SCHEMBL7182475 | 0.80 | ALDH1A1 (0.57) | KMT2AALDH1A1POLBLMNATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |