Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7180452 | 0.97 | ALDH1A1 (0.57) | ALDH1A1POLBKMT2ATLR8ESR1 | |
| Hydrochloric Acid SCHEMBL7178580 | 0.97 | ALDH1A1 (0.57) | ALDH1A1POLBKMT2ATLR8ESR1 | |
| Hydrochloric Acid SCHEMBL7182475 | 0.97 | ALDH1A1 (0.57) | ALDH1A1POLBKMT2ATLR8ESR1 | |
| Hydrochloric Acid SCHEMBL7178422 | 0.97 | ALDH1A1 (0.57) | ALDH1A1POLBKMT2ATLR8ESR1 | |
| Hydrochloric Acid SCHEMBL7182544 | 0.97 | ALDH1A1 (0.57) | ALDH1A1POLBKMT2ATLR8ESR1 | |
| SCHEMBL27908771 | 0.84 | POLB (0.57) | ALDH1A1POLBKMT2ATLR8ESR1 | |
| Hydrochloric Acid SCHEMBL7173136 | 0.83 | KMT2A (0.43) | ALDH1A1POLBKMT2ATLR8ESR1 | |
| SCHEMBL10005373 | 0.82 | ALDH1A1 (0.74) | ALDH1A1POLBKMT2ATLR8ESR1 | |
| Hydrochloric Acid SCHEMBL7175727 | 0.80 | KMT2A (0.43) | ALDH1A1POLBKMT2AESR1CYP3A4 | |
| Hydrochloric Acid SCHEMBL7177916 | 0.80 | KMT2A (0.43) | ALDH1A1POLBKMT2AESR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |