Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7173346 | 0.97 | PKM (0.65) | PKMALDH1A1HPGDKDM4ETSHR | |
| Hydrochloric Acid SCHEMBL7176318 | 0.97 | PKM (0.65) | PKMALDH1A1HPGDKDM4ETSHR | |
| Hydrochloric Acid SCHEMBL7181170 | 0.97 | PKM (0.65) | PKMALDH1A1HPGDKDM4ETSHR | |
| Hydrochloric Acid SCHEMBL7177159 | 0.97 | PKM (0.65) | PKMALDH1A1HPGDKDM4ETSHR | |
| Hydrochloric Acid SCHEMBL7180531 | 0.97 | PKM (0.65) | PKMALDH1A1HPGDKDM4ETSHR | |
| Hydrochloric Acid SCHEMBL7173332 | 0.97 | PKM (0.65) | PKMALDH1A1HPGDKDM4ETSHR | |
| Hydrochloric Acid SCHEMBL7175677 | 0.86 | POLB (0.51) | PKMALDH1A1HPGDKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL7180460 | 0.86 | PKM (0.50) | PKMALDH1A1HPGDKDM4ETSHR | |
| Hydrochloric Acid SCHEMBL7178837 | 0.85 | MAPT (0.59) | ALDH1A1HPGDKDM4ETSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL7173919 | 0.84 | PKM (0.50) | PKMALDH1A1HPGDKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |