Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7178467 | 0.97 | POLB (0.51) | POLBHDAC1HDAC8HDAC6L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7176360 | 0.97 | POLB (0.51) | POLBHDAC1HDAC8HDAC6L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7176648 | 0.97 | POLB (0.51) | POLBHDAC1HDAC8HDAC6L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7181491 | 0.97 | POLB (0.51) | POLBHDAC1HDAC8HDAC6L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7176838 | 0.97 | POLB (0.51) | POLBHDAC1HDAC8HDAC6L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7180433 | 0.97 | POLB (0.51) | POLBHDAC1HDAC8HDAC6L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7173138 | 0.86 | PKM (0.65) | POLBHDAC1HDAC8HDAC6L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7175894 | 0.86 | ALDH1A1 (0.45) | L3MBTL1HPGDKDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7178837 | 0.84 | MAPT (0.59) | POLBL3MBTL1HPGDKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7173332 | 0.84 | PKM (0.65) | POLBHDAC1HDAC8HDAC6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |