SCHEMBL7173145

SCHEMBL7173145

CC(=O)C1C(=O)C(C)N(c2ccccc2)C1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
MT-CO2 P00403 2/20 0.37
ALOX5 P09917 2/20 0.37
PKM P14618 2/20 0.37
HTT P42858 1/20 0.37
MAOA P21397 1/20 0.37
ABCB11 O95342 1/20 0.36
PTGS1 P23219 1/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
THRB P10828 1/20 0.36
HSD17B10 Q99714 1/20 0.36
LOX P28300 1/20 0.36
LOXL3 P58215 1/20 0.36
LOXL4 Q96JB6 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
KMT2A Q03164 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6713101 0.78 MAOA (0.48) LMNAALOX5MAOAALDH1A1MAPT
SCHEMBL9835334 0.76 MAOA (0.47) LMNAALOX5MAOAALDH1A1MAPT
SCHEMBL11376494 0.70 MT-CO2 (0.46) LMNAMT-CO2ALOX5PKMHTT
SCHEMBL11383378 0.68 MT-CO2 (0.38) LMNAMT-CO2ALOX5PKMHTT
SCHEMBL9185013 0.68 MT-CO2 (0.44) MT-CO2ALOX5PKMMAOAALDH1A1
SCHEMBL1027868 0.67 KMT2A (0.40) LMNAMT-CO2ALOX5PKMHTT
SCHEMBL10781678 0.66 SMN1; SMN2 (0.42) LMNAHTTABCB11PTGS1ALDH1A1
SCHEMBL10781686 0.66 SMN1; SMN2 (0.42) LMNAHTTABCB11PTGS1ALDH1A1
SCHEMBL10752342 0.66 DDB1 (0.44) MT-CO2ALOX5HTTKMT2AMEN1
SCHEMBL11379242 0.66 CACNA1B (0.45) MT-CO2ALOX5PKMMAOAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0826016-B1 STABILISED VINYL CHLORIDE POLYMER COMPOSITIONS AKCROS CHEM (GB) 2003-10-22 EP claimed
EP-0734414-B2 STABILISED VINYL CHLORIDE COMPOSITION AKCROS CHEM (GB) 2003-10-22 EP claimed
EP-0734414-B1 STABILISED VINYL CHLORIDE COMPOSITION AKCROS CHEM (GB) 1999-03-03 EP claimed
EP-0734414-A1 STABILISED VINYL CHLORIDE COMPOSITION AKCROS CHEMICALS (GB) 1996-10-02 EP claimed
WO-1995016739-A1 STABILISED VINYL CHLORIDE COMPOSITION AKCROS CHEMICALS (GB) 1995-06-22 WO claimed
EP-0734414-B2 STABILISED VINYL CHLORIDE COMPOSITION AKCROS CHEM (GB) 2003-10-22 EP disclosed
EP-0734414-B1 STABILISED VINYL CHLORIDE COMPOSITION AKCROS CHEM (GB) 1999-03-03 EP disclosed
US-5744525-A COMPRISING HOMOPOLYMER OR COPOLYMER OF VINYL CHLORIDE, ORGANOTIN SALT AND/OR DIVALENT METAL SALT OF CARBOXYLIC ACID OR PHENOL, HETEROCYCLIC COMPOUND AKROS CHEMICALS (GB) 1998-04-28 US disclosed
EP-0734414-A1 STABILISED VINYL CHLORIDE COMPOSITION AKCROS CHEMICALS (GB) 1996-10-02 EP disclosed
WO-1995016739-A1 STABILISED VINYL CHLORIDE COMPOSITION AKCROS CHEMICALS (GB) 1995-06-22 WO disclosed