Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7162165 | 0.74 | LTA4H (0.49) | LTA4HS1PR1S1PR3S1PR2LPAR2 | |
| SCHEMBL7166190 | 0.73 | S1PR1 (0.48) | LTA4HS1PR1S1PR3S1PR2LPAR2 | |
| SCHEMBL3368283 | 0.71 | LSS (0.56) | LTA4H | |
| SCHEMBL3291832 | 0.71 | HTT (0.65) | SMN1; SMN2HTTLMNATSHRALDH1A1 | |
| SCHEMBL3363347 | 0.70 | LSS (0.57) | — | |
| SCHEMBL5725957 | 0.67 | NPC1 (0.58) | S1PR1S1PR3S1PR2LPAR2SMN1; SMN2 | |
| SCHEMBL20988736 | 0.66 | S1PR2 (0.56) | LTA4HS1PR1S1PR3S1PR2LPAR2 | |
| SCHEMBL20534987 | 0.65 | CA12 (0.51) | ALDH1A1 | |
| SCHEMBL22690487 | 0.65 | CA2 (0.56) | TSHRALDH1A1 | |
| SCHEMBL8552037 | 0.65 | S1PR2 (0.47) | S1PR1S1PR3S1PR2LPAR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303503-A2 | ANILINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002006189-A2 | ANILINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-24 | — | — | WO | disclosed |