SCHEMBL7174168

SCHEMBL7174168

CCON=Cc1c(S(C)(=O)=O)ccc(C(=O)OC)c1Cl

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
TSHR P16473 2/20 0.35
KDM4E B2RXH2 2/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
VCAM1 P19320 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.33
CA2 P00918 3/20 0.33
CA1 P00915 2/20 0.33
CA9 Q16790 2/20 0.33
GAA P10253 2/20 0.33
CA5A P35218 1/20 0.33
ABL1 P00519 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7174163 1.00 ALDH1A1 (0.37) ALDH1A1TSHRKDM4EMAPTHPGD
SCHEMBL7081782 0.88 ALDH1A1 (0.36) ALDH1A1TSHRMAPTHPGDCYP1A2
SCHEMBL7168941 0.88 ALDH1A1 (0.36) ALDH1A1TSHRMAPTHPGDCYP1A2
SCHEMBL4267417 0.83 VCAM1 (0.37) ALDH1A1TSHRKDM4EMAPTHPGD
SCHEMBL4276213 0.83 VCAM1 (0.37) ALDH1A1TSHRKDM4EMAPTHPGD
SCHEMBL5835866 0.80 ALDH1A1 (0.42) ALDH1A1TSHRKDM4EMAPTHPGD
SCHEMBL4267428 0.79 VCAM1 (0.40) ALDH1A1TSHRKDM4EMAPTHPGD
SCHEMBL7172541 0.77 ALDH1A1 (0.34) ALDH1A1TSHRKDM4EMAPTHPGD
SCHEMBL7172556 0.77 ALDH1A1 (0.34) ALDH1A1TSHRKDM4EMAPTHPGD
SCHEMBL16164214 0.74 LMNA (0.32) TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6576596-B1 Compatible with crop plants BASF AKTIENGESELLSCHAFT (DE) 2003-06-10 US disclosed
US-6028035-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2000-02-22 US disclosed