Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | UGCG | Q16739 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5630376 | 0.80 | OPRK1 (0.75) | OPRK1CYP3A4CYP2C19OPRM1OPRD1 | |
| SCHEMBL5292681 | 0.73 | MEN1 (0.51) | MAPTKMT2AMEN1PKMALDH1A1 | |
| SCHEMBL18413066 | 0.73 | OPRK1 (0.56) | OPRK1KMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL3885673 | 0.73 | MEN1 (0.52) | MAPTNPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL6487344 | 0.71 | CYP1A2 (0.63) | MAPTKMT2AMEN1PKMALDH1A1 | |
| SCHEMBL997299 | 0.71 | CYP1A2 (0.63) | MAPTKMT2AMEN1PKMALDH1A1 | |
| Hydrochloric Acid SCHEMBL7670413 | 0.70 | OPRM1 (0.48) | MAPTOPRK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10434764 | 0.69 | NPC1 (0.55) | OPRK1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL28128070 | 0.69 | NPC1 (0.55) | OPRK1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL18197284 | 0.68 | RAB9A (0.54) | OPRK1KMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38133-E1 | N-Arylalkylenecarbonyl-N-methyl-benzylamine derivatives; analgesics, opioid agonists, antiinflammatory agents | ADOLOR CORPORATION | 2003-06-03 | — | — | US | disclosed |