Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776211 | 0.88 | ALDH1A1 (0.57) | ALDH1A1TSHRCYP3A4KDM4EPFKFB3 | |
| SCHEMBL28720827 | 0.87 | ALDH1A1 (0.40) | ALDH1A1TSHRCYP3A4KDM4EPFKFB3 | |
| SCHEMBL29716343 | 0.87 | ALDH1A1 (0.48) | ALDH1A1TSHRCYP3A4KDM4EPFKFB3 | |
| SCHEMBL8050048 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4KDM4EPFKFB3 | |
| SCHEMBL8051374 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4KDM4EPFKFB3 | |
| SCHEMBL7774846 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TSHRCYP3A4KDM4EPFKFB3 | |
| SCHEMBL27856998 | 0.77 | PCSK9 (0.52) | ALDH1A1TSHRCYP3A4KDM4EPFKFB3 | |
| SCHEMBL7776357 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TSHRCYP3A4KDM4EPFKFB3 | |
| SCHEMBL6926880 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TSHRCYP3A4KDM4EPFKFB3 | |
| SCHEMBL27922409 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TSHRCYP3A4KDM4EPFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030208071-A1 | Polyoxometalate catalysts for the preparation of sterically hindered N-substituted aryloxyamines | CIBA SPECIALTY CHEMICALS CORP. | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030208071-A1 | Polyoxometalate catalysts for the preparation of sterically hindered N-substituted aryloxyamines | KMO, PPOX, TAOK1 | ALDH1A1 4600/4885TSHR 1858/4885CYP3A4 1894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.