SCHEMBL7174875

SCHEMBL7174875

Cc1cc(C)c(C(=O)P(=O)(C(=O)c2c(COc3ccccc3)cccc2COc2ccccc2)c2ccccc2)c(C)c1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 2/20 0.40
PTGER1 P34995 1/20 0.40
PTGER3 P43115 1/20 0.40
PTGER2 P43116 1/20 0.40
MAOB P27338 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
USP2 O75604 1/20 0.39
MAPT P10636 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
FFAR1 O14842 3/20 0.38
FFAR4 Q5NUL3 2/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
SLC26A4 O43511 1/20 0.38
NPC1 O15118 1/20 0.38
NR4A2 P43354 1/20 0.38
RAB9A P51151 1/20 0.38
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7179536 0.88 PTGER1 (0.42) PTGER4PTGER1PTGER3PTGER2MAOB
SCHEMBL7182648 0.87 MEN1 (0.33) SMN1; SMN2L3MBTL1HPGDRAB9APOLB
SCHEMBL7177239 0.87 MAOB (0.47) PTGER4PTGER1PTGER3PTGER2MAOB
SCHEMBL7177172 0.85 NR4A2 (0.40) PTGER4PTGER1PTGER3PTGER2MAOB
SCHEMBL7181616 0.83 KMT2A (0.36) SMN1; SMN2USP2MAPTLMNAGAA
SCHEMBL7181175 0.81 NR4A2 (0.45) PTGER4PTGER1PTGER3PTGER2MAOB
SCHEMBL7177289 0.81 L3MBTL1 (0.34) USP2MAPTL3MBTL1LMNAHPGD
SCHEMBL7174855 0.81 GFER (0.35) SMN1; SMN2USP2MAPTLMNAGAA
SCHEMBL7180464 0.81 KMT2A (0.34) SMN1; SMN2USP2MAPTLMNAGAA
SCHEMBL7181283 0.80 L3MBTL1 (0.40) MAPTL3MBTL1HPGDRAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 PTGER4 3439/4885PTGER1 3015/4885PTGER3 2637/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 PTGER4 3784/4885PTGER1 3796/4885PTGER3 2833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.