SCHEMBL7177239

SCHEMBL7177239

Cc1cccc(C)c1C(=O)P(=O)(C(=O)c1c(COc2ccccc2)cccc1COc1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.47
FFAR1 O14842 5/20 0.43
FFAR4 Q5NUL3 2/20 0.43
PTGER1 P34995 1/20 0.41
PTGER4 P35408 1/20 0.41
PTGER3 P43115 1/20 0.41
PTGER2 P43116 1/20 0.41
SLC26A4 O43511 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.40
PTPRC P08575 1/20 0.40
PTPN1 P18031 1/20 0.40
USP2 O75604 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
S1PR1 P21453 1/20 0.40
S1PR5 Q9H228 1/20 0.40
HPGD P15428 2/20 0.39
ALDH1A1 P00352 1/20 0.39
ALOX12 P18054 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7181175 0.92 NR4A2 (0.45) MAOBFFAR1FFAR4PTGER1PTGER4
SCHEMBL7179536 0.91 PTGER1 (0.42) MAOBFFAR1FFAR4PTGER1PTGER4
SCHEMBL7177172 0.88 NR4A2 (0.40) MAOBFFAR1FFAR4PTGER1PTGER4
SCHEMBL7174875 0.87 PTGER4 (0.40) MAOBFFAR1FFAR4PTGER1PTGER4
SCHEMBL7188206 0.85 PTGS2 (0.40) SMN1; SMN2L3MBTL1HPGDALDH1A1ALOX12
SCHEMBL7181601 0.85 KDM4E (0.47) FFAR1PTGER1PTGER4PTGER3PTGER2
SCHEMBL7187675 0.84 NR4A2 (0.50) MAOBPTGER1PTGER4PTGER3PTGER2
SCHEMBL246249 0.83 L3MBTL1 (0.41) KDM4EUSP2L3MBTL1HPGDALDH1A1
SCHEMBL7723212 0.82 TDP1 (0.43) FFAR1FFAR4PTGER1PTGER4PTGER3
SCHEMBL7182129 0.81 MAOB (0.49) MAOBFFAR1FFAR4PTGER1PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 MAOB 4189/4885FFAR1 671/4885FFAR4 1611/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 MAOB 4319/4885FFAR1 711/4885FFAR4 1526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.