Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26557740 | 0.66 | OPRM1 (0.41) | DNM1OPRM1OPRL1 | |
| SCHEMBL17351055 | 0.66 | DNM1 (0.48) | DNM1OPRM1OPRL1 | |
| SCHEMBL27769660 | 0.62 | — | — | |
| SCHEMBL14679618 | 0.60 | DNM1 (0.52) | DNM1 | |
| SCHEMBL24688639 | 0.60 | OPRM1 (0.43) | DNM1OPRM1OPRL1 | |
| SCHEMBL15486339 | 0.60 | DNM1 (0.67) | DNM1 | |
| SCHEMBL20544016 | 0.59 | DNM1 (0.43) | DNM1 | |
| SCHEMBL332622 | 0.59 | DNM1 (0.44) | DNM1 | |
| SCHEMBL8520421 | 0.57 | DNM1 (0.48) | DNM1 | |
| Cyclohexane SCHEMBL9836640 | 0.57 | DNM1 (0.79) | DNM1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334094-A1 | CHOLESTEROL LOWERING BENZO[B]THIOPHENES AND BENZO[D]ISOTHIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002036584-A1 | CHOLESTEROL LOWERING BENZO`B! THIOPHENES AND BENZO`D! ISOTHIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-05-10 | — | — | WO | disclosed |