SCHEMBL7176263

SCHEMBL7176263

FC1=C(F)c2c(cc(-c3cc(F)ccc3F)c(F)c2F)[CH]1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA3 P07451 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7182615 0.83 CTSL (0.30)
SCHEMBL7180703 0.76
SCHEMBL6287374 0.72
SCHEMBL9766850 0.71 CA9 (0.52) CA3CA6CA5ACA9CA14
SCHEMBL6278022 0.69 CA9 (0.42) CA3CA6CA5ACA9CA14
SCHEMBL6283683 0.68
SCHEMBL24766983 0.59 CA3 (0.44) CA3CA6CA5ACA9CA14
SCHEMBL19133130 0.58 CA9 (0.39) CA3CA6CA5ACA9CA14
SCHEMBL30927149 0.58 ALDH1A1 (0.50) CA3CA6CA5ACA9CA14
SCHEMBL24254696 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1349653-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2003-10-08 EP disclosed
WO-2002036639-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-05-10 WO disclosed