SCHEMBL71781

SCHEMBL71781

O=C(O)[C@@H](Cc1ccccc1)NC(F)(F)F

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACE P12821 2/20 0.56
NPSR1 Q6W5P4 1/20 0.55
FPR2 P25090 2/20 0.54
ECE1 P42892 1/20 0.54
MME P08473 2/20 0.53
CPA1 P15085 1/20 0.50
NAALAD2 Q9Y3Q0 1/20 0.50
CYP1A2 P05177 1/20 0.50
MMP2 P08253 4/20 0.49
MMP9 P14780 3/20 0.49
ALDH1A1 P00352 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
ADAMTS4 O75173 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL933401 1.00 ACE (0.56) ACENPSR1FPR2ECE1MME
SCHEMBL71782 1.00 ACE (0.56) ACENPSR1FPR2ECE1MME
SCHEMBL8823272 0.86 ACE (0.58) ACEMMECPA1NAALAD2L3MBTL1
SCHEMBL21326281 0.86 EPHX1 (0.49) ACENPSR1FPR2ECE1CPA1
SCHEMBL21326284 0.86 EPHX1 (0.49) ACENPSR1FPR2ECE1CPA1
SCHEMBL8823270 0.86 ACE (0.58) ACEMMECPA1NAALAD2L3MBTL1
SCHEMBL29022675 0.85 FPR2 (0.50) ACENPSR1FPR2MMEMMP2
SCHEMBL6402000 0.85 SLC7A5 (0.56) ACEALDH1A1
SCHEMBL6401999 0.85 SLC7A5 (0.56) ACEALDH1A1
SCHEMBL5772094 0.83 ATM (0.57) ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1564 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3334759-B1 LACTOFERRIN FRAGMENT FOR THE USE AS ANTIBACTERIAL AND ANTIVIRAL AGENT FARMAGENS HEALTH CARE SRL (IT) 2019-09-04 EP claimed
EP-3334759-A1 LACTOFERRIN FRAGMENT FOR THE USE AS ANTIBACTERIAL AND ANTIVIRAL AGENT Farmagens Health Care Srl (IT) 2018-06-20 EP claimed
WO-2017025846-A1 LACTOFERRIN FRAGMENT FOR THE USE AS ANTIBACTERIAL AND ANTIVIRAL AGENT FARMAGENS HEALTH CARE SRL (IT) 2017-02-16 WO claimed
US-20030143664-A1 Products of manufacture and processes for peptide synthesis DIVERSA CORPORATION (US) 2003-07-31 US claimed
WO-2003048189-A2 PRODUCTS OF MANUFACTURE AND PROCESSES FOR PEPTIDE SYNTHESIS DIVERSA CORPORATION (US) 2003-06-12 WO claimed
US-12037386-B2 Antibodies to PfGARP kill Plasmodium falciparum malaria parasites and protect against infection and severe disease RHODE ISLAND HOSPITAL (US) 2024-07-16 US disclosed
CN-113967258-B FAP-activated therapeutic agents and related uses 塔夫茨大学信托人 2024-07-02 CN disclosed
US-12023316-B2 FAP-activated therapeutic agents, and uses related thereto BACH BIOSCIENCES, LLC (US) 2024-07-02 US disclosed
EP-4389757-A2 METHODS FOR PURIFYING ANTIBODIES GlaxoSmithKline Intellectual Property Development Limited (GB) 2024-06-26 EP disclosed
WO-2024129720-A2 T CELL RECEPTOR CONSTRUCTS AND USES THEREOF BIONTECH US INC. (US) 2024-06-20 WO disclosed
CN-118076632-A Conditionally active proteins for neurodegenerative diseases 生物蛋白有限公司 2024-05-24 CN disclosed
EP-3510042-B1 METHODS FOR PURIFYING ANTIBODIES GLAXOSMITHKLINE IP DEV LTD (GB) 2024-05-22 EP disclosed
US-5508384-A NEUROLEPTIC AGENTS WITH REDUCED SIDE EFFECTS NEW YORK UNIVERSITY (US) 1996-04-16 US disclosed
WO-1995022561-A2 PEPTIDES RECOGNIZED BY MELANOMA-SPECIFIC CYTOTOXIC LYMPHOCYTES, AND USES THEREFOR UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 1995-08-24 WO disclosed
WO-1995020397-A1 PHOSPHACAN, NUCLEIC ACIDS ENCODING THEREOF AND ANTIBODIES THERETO NEW YORK UNIVERSITY (US) 1995-08-03 WO disclosed
WO-1995013828-A1 BENEFICIAL WOUND HEALING APPLICATIONS OF CALRETICULIN AND OTHER HYALURONAN-ASSOCIATED PROTEINS NEW YORK UNIVERSITY (US) 1995-05-26 WO disclosed
WO-1995013291-A1 NEURON-GLIA CELL ADHESION MOLECULE, NG-CAM, IN TREATMENT OF NERVE DAMAGE NEW YORK UNIVERSITY (US) 1995-05-18 WO disclosed
WO-1994005695-A9 POLYPEPTIDES OF G-COUPLED RECEPTOR PROTEINS, AND COMPOSITIONS AND METHODS THEREOF 1994-05-11 WO disclosed
WO-1994003601-A9 CLONING, EXPRESSION AND USES FOR NEUROCAN AS A CHONDROITIN SULFATE PROTEOGLYCAN 1994-03-31 WO disclosed
WO-1994003601-A2 CLONING, EXPRESSION AND USES FOR NEUROCAN AS A CHONDROITIN SULFATE PROTEOGLYCAN NEW YORK UNIVERSITY (US) 1994-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12023316-B2 FAP-activated therapeutic agents, and uses related thereto FAP, FIBP, GOT1 ACE 319/4885NPSR1 4325/4885FPR2 1276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.