Tetraphenylphosphonium

Tetraphenylphosphonium

SCHEMBL7178151

O=S([O-])[O-].[H+].c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.39

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.39
HIF1A Q16665 1/20 0.36
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
CYP1A2 P05177 3/20 0.32
CYP2C19 P33261 2/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.32
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetraphenylphosphonium SCHEMBL7178157 0.87 EPHX2 (0.37) EPHX2HIF1ACES2CES1CYP1A2
Tetraphenylphosphonium SCHEMBL11146104 0.81 HIF1A (0.38) HIF1ACES2CES1CYP1A2CYP2C19
Tetraphenylphosphonium SCHEMBL7935005 0.80 HIF1A (0.45) HIF1ACYP1A2CYP2C19ALDH1A1CYP2D6
Tetraphenylphosphonium SCHEMBL7934968 0.80 HIF1A (0.45) HIF1ACYP1A2CYP2C19ALDH1A1CYP2D6
Tetraphenylphosphonium SCHEMBL7931760 0.80 HIF1A (0.45) HIF1ACYP1A2CYP2C19ALDH1A1CYP2D6
Tetraphenylphosphonium SCHEMBL18936425 0.80 HIF1A (0.45) HIF1ACYP1A2CYP2C19ALDH1A1CYP2D6
Tetraphenylphosphonium SCHEMBL7906432 0.80 HIF1A (0.45) HIF1ACYP1A2CYP2C19ALDH1A1CYP2D6
Tetraphenylphosphonium SCHEMBL3300848 0.80 HIF1A (0.45) HIF1ACYP1A2CYP2C19ALDH1A1CYP2D6
Tetraphenylphosphonium SCHEMBL29362652 0.80 HIF1A (0.50) HIF1ACYP1A2CYP2C19ALDH1A1CYP2D6
Tetraphenylphosphonium SCHEMBL7172564 0.79 ALDH1A1 (0.39) EPHX2HIF1ACYP1A2CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1275694-A1 AROMATIC POLYCARBONATE COMPOSITION, PROCESS FOR PRODUCING THE SAME, AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2003-01-15 EP disclosed
US-20020103328-A1 Aromatic polycarbonate composition, production process therefor and molded product thereof TEIJIN LIMITED 2002-08-01 US disclosed