Tetraphenylphosphonium

Tetraphenylphosphonium

SCHEMBL3300848

[F-].[F-].[H+].c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.45
ALDH1A1 P00352 5/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MGLL Q99685 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TSHR P16473 5/20 0.33
DPP4 P27487 2/20 0.33
MTOR P42345 1/20 0.33
RAB9A P51151 1/20 0.33
GRM7 Q14831 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
F2 P00734 1/20 0.33
CYP3A4 P08684 1/20 0.32
ALOX15 P16050 1/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetraphenylphosphonium SCHEMBL7906432 1.00 HIF1A (0.45) HIF1AALDH1A1MAPTHPGDSMN1; SMN2
Tetraphenylphosphonium SCHEMBL585136 0.96 HIF1A (0.47) HIF1AALDH1A1MAPTHPGDSMN1; SMN2
Tetraphenylphosphonium SCHEMBL7935005 0.93 HIF1A (0.45) HIF1AALDH1A1MAPTHPGDSMN1; SMN2
Tetraphenylphosphonium SCHEMBL7931760 0.93 HIF1A (0.45) HIF1AALDH1A1MAPTHPGDSMN1; SMN2
Tetraphenylphosphonium SCHEMBL3304548 0.93 HIF1A (0.45) HIF1AALDH1A1MAPTHPGDSMN1; SMN2
Tetraphenylphosphonium SCHEMBL7934968 0.93 HIF1A (0.45) HIF1AALDH1A1MAPTHPGDSMN1; SMN2
Tetraphenylphosphonium SCHEMBL18936425 0.93 HIF1A (0.45) HIF1AALDH1A1MAPTHPGDSMN1; SMN2
Tetraphenylphosphonium SCHEMBL29362652 0.93 HIF1A (0.50) HIF1AALDH1A1MAPTHPGDSMN1; SMN2
Tetraphenylphosphonium SCHEMBL9547828 0.90 HIF1A (0.43) HIF1AALDH1A1MAPTHPGDSMN1; SMN2
Tetraphenylphosphonium SCHEMBL7931797 0.90 HIF1A (0.43) HIF1AALDH1A1MAPTHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3178811-B1 A PROCESS FOR THE SYNTHESIS OF SULFONES AND SULFONAMIDES COMMISSARIAT ENERGIE ATOMIQUE (FR) 2018-10-31 EP claimed
US-20170166542-A1 Process for the Synthesis of Sulfones and Sulfonamides COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2017-06-15 US claimed
EP-3178811-A1 A PROCESS FOR THE SYNTHESIS OF SULFONES AND SULFONAMIDES COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (FR) 2017-06-14 EP claimed
EP-0187023-B1 PROCESS FOR THE PREPARATION OF ORGANIC FLUORIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-08-09 EP claimed
CN-117160497-B Catalyst and method for preparing hexafluoropropylene dimer 北京宇极科技发展有限公司 2024-03-08 CN disclosed
CN-117504902-A Catalyst and method for preparing hexafluoropropylene dimer 泉州宇极新材料科技有限公司 2024-02-06 CN disclosed
CN-117160497-A Catalyst and method for preparing hexafluoropropylene dimer 北京宇极科技发展有限公司 2023-12-05 CN disclosed
US-10173993-B2 Process for the synthesis of sulfones and sulfonamides COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2019-01-08 US disclosed
EP-3178811-B1 A PROCESS FOR THE SYNTHESIS OF SULFONES AND SULFONAMIDES COMMISSARIAT ENERGIE ATOMIQUE (FR) 2018-10-31 EP disclosed
US-20170166542-A1 Process for the Synthesis of Sulfones and Sulfonamides COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2017-06-15 US disclosed
EP-3178811-A1 A PROCESS FOR THE SYNTHESIS OF SULFONES AND SULFONAMIDES COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (FR) 2017-06-14 EP disclosed
US-20100096585-A1 Process for Preparing 2,6-Dichloro-4-(Trifluoromethyl)Phenylhydrazine Using Mixtures of Dichloro-Fluoro-Trifluoromethylbenzenes BASF SE (DE) 2010-04-22 US disclosed
US-6498267-B2 PREPARATION OF PYRETHROIDS. AVENTIS CROPSCIENCE GMBH (DE) 2002-12-24 US disclosed
US-20020045766-A1 5-halo-4-fluoro-4,7,7-trimethyl-3-oxabicyclo[4.1.0]heptan-2-ones, process for their preparation and their use for preparing cyclopropanecarboxylic acids DEMOUTE JEAN PIERRE (DE) 2002-04-18 US disclosed
US-6337407-B1 HALOGENATED COMPOUNDS WITH HETEROCYCLIC ESTER COMPOUNDS AVENTIS CROPSCIENCE GMBH (DE) 2002-01-08 US disclosed
EP-0604955-B1 Preparation of hexafluoropropene oligomers MINNESOTA MINING & MFG (US) 1997-09-24 EP disclosed
EP-0604955-A2 Preparation of hexafluoropropene oligomers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-07-06 EP disclosed
US-5315043-A Potassium, cesium, rubidium fluorides and hydrofluoric acid E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-05-24 US disclosed
US-5254774-A Using catalyst and aprotic solvent MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-10-19 US disclosed
EP-0187023-B1 PROCESS FOR THE PREPARATION OF ORGANIC FLUORIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-08-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170166542-A1 Process for the Synthesis of Sulfones and Sulfonamides STS, SULT2A1, TST HIF1A 963/4885ALDH1A1 2456/4885MAPT 4101/4885
US-20020045766-A1 5-halo-4-fluoro-4,7,7-trimethyl-3-oxabicyclo[4.1.0]heptan-2-ones, process for their preparation and their use for preparing cyclopropanecarboxylic acids CYP8B1, CYP4B1, CYP4F11 HIF1A 1909/4885ALDH1A1 521/4885MAPT 2891/4885
US-10173993-B2 Process for the synthesis of sulfones and sulfonamides STS, SULT2A1, TST HIF1A 963/4885ALDH1A1 2456/4885MAPT 4101/4885
US-20100096585-A1 Process for Preparing 2,6-Dichloro-4-(Trifluoromethyl)Phenylhydrazine Using Mixtures of Dichloro-Fluoro-Trifluoromethylbenzenes DAZAP1, CYP4Z1, CYP2F1 HIF1A 402/4885ALDH1A1 93/4885MAPT 1980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.