Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTPRA | P18433 | 1/20 | 0.45 |
| ▸ | PTPRB | P23467 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.42 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.39 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL373234 | 1.00 | CYP1A2 (0.48) | CYP1A2ALDH1A1HIF1ACYP2C9TSHR | |
| SCHEMBL373500 | 0.93 | CYP1A2 (0.42) | CYP1A2ALDH1A1HIF1ACYP2C9TSHR | |
| SCHEMBL718829 | 0.86 | MAPT (0.47) | CYP1A2ALDH1A1HIF1AMAPK1PRMT1 | |
| SCHEMBL1802886 | 0.86 | MAPT (0.47) | CYP1A2ALDH1A1HIF1AMAPK1PRMT1 | |
| SCHEMBL373229 | 0.86 | MAPT (0.47) | CYP1A2ALDH1A1HIF1AMAPK1PRMT1 | |
| SCHEMBL373328 | 0.86 | MAPT (0.47) | CYP1A2ALDH1A1HIF1AMAPK1PRMT1 | |
| SCHEMBL13609825 | 0.85 | CYP1A2 (0.43) | CYP1A2ALDH1A1HIF1ACYP2C9TSHR | |
| SCHEMBL7179907 | 0.84 | CYP1A2 (0.48) | CYP1A2ALDH1A1HIF1ACYP2C9TSHR | |
| SCHEMBL7179903 | 0.84 | CYP1A2 (0.48) | CYP1A2ALDH1A1HIF1ACYP2C9TSHR | |
| SCHEMBL7178612 | 0.77 | CYP1A2 (0.42) | CYP1A2ALDH1A1HIF1ACYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722110-B1 | Water absorptive soft contact lens | MENICON CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-5661194-A | POLYMER FROM MONOMERS OF (METH)ACRYLAMIDE TYPE MONOMER, FLUOROALKYL (SILICON-CONTAINING ALKYL) FUMARATE MONOMER, AND CROSSLINKING MONOMER | MENICON CO., LTD. (JP) | 1997-08-26 | — | — | US | disclosed |
| EP-0722110-A2 | Water absorptive soft contact lens | Menicon Co., Ltd. (JP) | 1996-07-17 | — | — | EP | disclosed |