SCHEMBL373328

SCHEMBL373328

C=C(C)C(=O)Oc1cc2ccccc2c(N=Nc2ccccc2)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 9/20 0.47
▸ MEN1 O00255 7/20 0.47
▸ KMT2A Q03164 7/20 0.47
▸ ALDH1A1 P00352 4/20 0.47
▸ L3MBTL1 Q9Y468 4/20 0.47
▸ POLB P06746 3/20 0.47
▸ MAPK1 P28482 3/20 0.47
▸ RECQL P46063 2/20 0.47
▸ NPC1 O15118 2/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ IDO1 P14902 1/20 0.47
▸ CASP6 P55212 1/20 0.47
▸ CTDSP1 Q9GZU7 1/20 0.47
▸ TDP1 Q9NUW8 3/20 0.46
▸ MITF O75030 1/20 0.46
▸ USP2 O75604 1/20 0.46
▸ THRB P10828 3/20 0.45
▸ NQO2 P16083 1/20 0.42
▸ PKM P14618 2/20 0.41
▸ CASP3 P42574 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1802886 1.00 MAPT (0.47) MAPTMEN1KMT2AALDH1A1L3MBTL1
SCHEMBL373229 1.00 MAPT (0.47) MAPTMEN1KMT2AALDH1A1L3MBTL1
SCHEMBL718829 1.00 MAPT (0.47) MAPTMEN1KMT2AALDH1A1L3MBTL1
SCHEMBL626265 0.86 KMT2A (0.52) MAPTMEN1KMT2AALDH1A1L3MBTL1
SCHEMBL7179285 0.86 CYP1A2 (0.48) MAPTMEN1KMT2AALDH1A1L3MBTL1
SCHEMBL373234 0.86 CYP1A2 (0.48) MAPTMEN1KMT2AALDH1A1L3MBTL1
SCHEMBL13609833 0.85 THRB (0.50) MAPTMEN1KMT2AALDH1A1L3MBTL1
SCHEMBL7830817 0.85 MEN1 (0.41) MAPTMEN1KMT2AALDH1A1L3MBTL1
SCHEMBL373500 0.84 CYP1A2 (0.42) MAPTMEN1KMT2AALDH1A1L3MBTL1
SCHEMBL13609828 0.84 THRB (0.51) MAPTMEN1KMT2AALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1030194-B1 Material for a soft intraocular lens MENICON CO LTD (JP) 2002-12-04 — — EP claimed
US-6326448-B1 HYDROPHILIC MONOMER; LENSES MENICON CO., LTD. (JP) 2001-12-04 — — US claimed
US-6277940-B1 TRANSPARENCY AND FLEXIBILITY, REFRACTIVE INDEX, CAN BE INSERTED FROM A SMALL INCISION MENICON CO. LTD (JP) 2001-08-21 — — US claimed
EP-1030194-A1 Material for a soft intraocular lens Menicon Co., Ltd. (JP) 2000-08-23 — — EP claimed
WO-2023068316-A1 MATERIAL FOR SOFT CONTACT LENS HAVING CONTRAST IMPROVEMENT FUNCTION 興和株式会社 2023-04-27 — — WO disclosed
US-20210163650-A1 POLYMER MATERIAL MENICON CO., LTD. (JP) 2021-06-03 — — US disclosed
EP-3822296-A1 POLYMER MATERIAL Menicon Co., Ltd. (JP) 2021-05-19 — — EP disclosed
EP-3086162-B1 OCULAR LENS MENICON CO LTD (JP) 2019-04-17 — — EP disclosed
US-20180356561-A1 GEL, GEL MANUFACTURING METHOD, LENS, CONTACT LENS SURFACE MODIFIER, POLYMERIZABLE COMPOSITION, AND POLYMER JSR CORPORATION (JP) 2018-12-13 — — US disclosed
EP-3086163-B1 POLYSILOXANE-BASED MACROMONOMER FOR USE IN OCULAR LENS AND OCULAR LENS USING SAME MENICON CO LTD (JP) 2018-11-14 — — EP disclosed
EP-2857459-B1 STABLE POLYMERIZABLE UV-ABSORBING COLORANT FOR INTRAOCULAR LENS KOWA CO (JP) 2017-12-27 — — EP disclosed
US-9657131-B2 Ophthalmic lens MENICON CO., LTD. (JP) 2017-05-23 — — US disclosed
US-5346946-A Polysiloxane macromonomer MENICON CO., LTD (JP) 1994-09-13 — — US disclosed
EP-0600269-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1994-06-08 — — EP disclosed
EP-0584826-A2 Ocular lens material Menicon Co., Ltd. (JP) 1994-03-02 — — EP disclosed
EP-0584764-A1 Ocular lens material Menicon Co., Ltd. (JP) 1994-03-02 — — EP disclosed
EP-0578087-A2 Ocular lens material Menicon Co., Ltd. (JP) 1994-01-12 — — EP disclosed
US-5041511-A Vinyl benzene acrylate or methacrylate crosslinking agent MENICON CO., LTD. (JP) 1991-08-20 — — US disclosed
US-4954586-A COPOLYMER OF A FLUORINE CONTAINING (METH)ACRYLATE, AN ALKYL (METH)ACRYLATE, A POLYSILOXANE AND A URETHANE CONTAINING POLYSILOXANE MENICON CO., LTD (JP) 1990-09-04 — — US disclosed
EP-0379146-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1990-07-25 — — EP disclosed
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