Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 5/20 | 0.56 |
| ▸ | LDHB | P07195 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7174190 | 0.82 | LDHA (0.67) | LDHALDHBKMT2AMEN1POLB | |
| SCHEMBL7176330 | 0.81 | LDHA (0.59) | LDHALDHBKMT2AMEN1POLB | |
| SCHEMBL7186216 | 0.80 | LDHA (0.62) | LDHALDHBKMT2AMEN1POLB | |
| SCHEMBL7186222 | 0.78 | LDHA (0.62) | LDHALDHBKMT2AMEN1POLB | |
| SCHEMBL10706989 | 0.76 | LDHA (0.67) | LDHALDHBKMT2AMEN1MAPT | |
| SCHEMBL6846916 | 0.76 | LDHA (0.61) | LDHALDHBKMT2AMEN1POLB | |
| SCHEMBL11044033 | 0.74 | ALDH1A1 (0.48) | KMT2AMEN1POLBHPGDMAPT | |
| SCHEMBL353909 | 0.73 | MEN1 (0.43) | LDHALDHBKMT2AMEN1POLB | |
| SCHEMBL2622272 | 0.73 | ALB (0.65) | LDHALDHBKMT2AMEN1POLB | |
| SCHEMBL2757193 | 0.72 | MEN1 (0.43) | LDHALDHBKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980350-A4 | HYDROXYNAPHTHOIC ACIDS AND DERIVATIVES | UNIV NEW MEXICO (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6124498-A | Hydroxynaphthoic acids and derivatives | UNIVERSITY OF NEW MEXICO (US) | 2000-09-26 | — | — | US | disclosed |
| EP-0980350-A2 | HYDROXYNAPHTHOIC ACIDS AND DERIVATIVES | The University of New Mexico (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049130-A2 | HYDROXYNAPHTHOIC ACIDS AND DERIVATIVES | THE UNIVERSITY OF NEW MEXICO (US) | 1998-11-05 | — | — | WO | disclosed |