Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 9/20 | 0.67 |
| ▸ | LDHB | P07195 | 8/20 | 0.67 |
| ▸ | ALB | P02768 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665238 | 0.90 | LDHA (0.54) | LDHALDHBALBCYP3A4ACHE | |
| SCHEMBL7183958 | 0.81 | LDHA (1.00) | LDHALDHBALBCYP3A4ACHE | |
| SCHEMBL6846916 | 0.80 | LDHA (0.61) | LDHALDHBALBCYP3A4ACHE | |
| SCHEMBL7179558 | 0.76 | LDHA (0.56) | LDHALDHBALBCYP3A4ALDH1A1 | |
| SCHEMBL113091 | 0.75 | PDE10A (0.62) | LDHALDHBPDE10AALDH1A1TSHR | |
| SCHEMBL1257863 | 0.75 | CYP3A4 (0.50) | LDHALDHBCYP3A4ACHEALDH1A1 | |
| SCHEMBL842692 | 0.74 | NOTUM (0.42) | LDHALDHBCYP3A4ACHEPDE10A | |
| SCHEMBL238022 | 0.74 | LDHA (0.48) | LDHALDHBCYP3A4ACHEALDH1A1 | |
| SCHEMBL8106142 | 0.74 | CYP3A4 (0.54) | LDHALDHBCYP3A4ACHEALDH1A1 | |
| SCHEMBL11376422 | 0.73 | LDHA (0.44) | LDHALDHBALBCYP3A4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180201629-A1 | SEPARATION OF METAL-ORGANIC FRAMEWORKS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2018-07-19 | — | — | US | disclosed |
| US-10010860-B2 | Production of metal-organic frameworks | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2018-07-03 | — | — | US | disclosed |
| US-9630163-B2 | Production of metal-organic frameworks | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2017-04-25 | — | — | US | disclosed |
| US-20160346757-A1 | Production of metal-organic frameworks | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2016-12-01 | — | — | US | disclosed |
| US-20160347774-A1 | PRODUCTION OF METAL-ORGANIC FRAMEWORKS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2016-12-01 | — | — | US | disclosed |
| US-20160346756-A1 | PRODUCTION OF METAL-ORGANIC FRAMEWORKS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2016-12-01 | — | — | US | disclosed |
| US-9139601-B2 | Crystallisation facilitators for the synthesis of metal organic frameworks | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2015-09-22 | — | — | US | disclosed |
| US-20130204025-A1 | CRYSTALLISATION FACILITATORS FOR THE SYNTHESIS OF METAL ORGANIC FRAMEWORKS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2013-08-08 | — | — | US | disclosed |
| US-8500889-B2 | Gas adsorption material | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2013-08-06 | — | — | US | disclosed |
| US-7799120-B2 | Metal-organic frameworks with exceptionally high capacity for storage of carbon dioxide at room-temperature | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-09-21 | — | — | US | disclosed |
| US-4643925-A | PACKAGING FOODS AND BEVERAGES, CANS AND BOTTLES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1987-02-17 | — | — | US | disclosed |
| EP-0105016-B1 | POLYISOPHTHALATE AND COPOLYMERS THEREOF HAVING REDUCED CYCLIC DIMER CONTENT, AND A PROCESS FOR MAKING THE SAME | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1987-01-21 | — | — | EP | disclosed |
| US-4604257-A | POLYESTERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-08-05 | — | — | US | disclosed |
| US-4482586-A | Multi-layer polyisophthalate and polyterephthalate articles and process therefor | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-11-13 | — | — | US | disclosed |
| EP-0105824-A1 | Polyisophthalates and copolymers thereof having high barrier properties | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-04-18 | — | — | EP | disclosed |
| EP-0105825-A2 | Multi-layer polyisophthalate and polyterephthalate articles and process therefor | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-04-18 | — | — | EP | disclosed |
| EP-0105016-A1 | Polyisophthalate and copolymers thereof having reduced cyclic dimer content, and a process for making the same | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-04-04 | — | — | EP | disclosed |
| US-4424337-A | Polyisophthalate and copolymers thereof having reduced cyclic dimer content, and a process for making the same | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-01-03 | — | — | US | disclosed |
| US-4418188-A | PROTONIC ACID CATALYSTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1983-11-29 | — | — | US | disclosed |
| US-4403090-A | Polyisophthalates and copolymers thereof having high barrier properties | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1983-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160346756-A1 | PRODUCTION OF METAL-ORGANIC FRAMEWORKS | OAT, CYP4F2, OSTC | LDHA 421/4885LDHB 952/4885ALB 91/4885 |
| US-20160346757-A1 | Production of metal-organic frameworks | OAT, CYP4F2, OSTC | LDHA 421/4885LDHB 952/4885ALB 91/4885 |
| US-20130204025-A1 | CRYSTALLISATION FACILITATORS FOR THE SYNTHESIS OF METAL ORGANIC FRAMEWORKS | MACF1, POF1B, MYB | LDHA 3152/4885LDHB 3703/4885ALB 902/4885 |
| US-20180201629-A1 | SEPARATION OF METAL-ORGANIC FRAMEWORKS | HNRNPF, HNRNPU, PUF60 | LDHA 2828/4885LDHB 3399/4885ALB 110/4885 |
| US-20160347774-A1 | PRODUCTION OF METAL-ORGANIC FRAMEWORKS | OAT, CYP4F2, OSTC | LDHA 421/4885LDHB 952/4885ALB 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.