Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 10/20 | 1.00 |
| ▸ | LDHB | P07195 | 9/20 | 1.00 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7183463 | 0.85 | LDHA (1.00) | LDHALDHB | |
| SCHEMBL233361 | 0.83 | LDHA (1.00) | LDHALDHBPTPN1PTPN2PTPN6 | |
| SCHEMBL30417934 | 0.83 | LDHA (1.00) | LDHALDHBPTPN1PTPN2PTPN6 | |
| SCHEMBL7174190 | 0.80 | LDHA (0.67) | LDHALDHBCNR2GPR55 | |
| SCHEMBL7183958 | 0.80 | LDHA (1.00) | LDHALDHB | |
| SCHEMBL15322250 | 0.78 | LDHA (0.82) | LDHALDHBPTPN1PTPN2PTPN6 | |
| SCHEMBL7180825 | 0.78 | LDHA (0.86) | LDHALDHBCNR2GPR55 | |
| SCHEMBL7179527 | 0.78 | LDHA (0.86) | LDHALDHBBCL2L1 | |
| SCHEMBL7187931 | 0.76 | LDHA (0.87) | LDHALDHBCNR2GPR55BCL2 | |
| SCHEMBL7179610 | 0.76 | LDHA (1.00) | LDHALDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980350-A4 | HYDROXYNAPHTHOIC ACIDS AND DERIVATIVES | UNIV NEW MEXICO (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6124498-A | Hydroxynaphthoic acids and derivatives | UNIVERSITY OF NEW MEXICO (US) | 2000-09-26 | — | — | US | disclosed |
| EP-0980350-A2 | HYDROXYNAPHTHOIC ACIDS AND DERIVATIVES | The University of New Mexico (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049130-A2 | HYDROXYNAPHTHOIC ACIDS AND DERIVATIVES | THE UNIVERSITY OF NEW MEXICO (US) | 1998-11-05 | — | — | WO | disclosed |