Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 15/20 | 1.00 |
| ▸ | LDHB | P07195 | 14/20 | 1.00 |
| ▸ | ALB | P02768 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.42 |
| ▸ | GLRB | P48167 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10706989 | 0.81 | LDHA (0.67) | LDHALDHBALBCYP3A4ACHE | |
| SCHEMBL7179562 | 0.80 | LDHA (1.00) | LDHALDHB | |
| SCHEMBL7181495 | 0.79 | LDHA (1.00) | LDHALDHBALBGLRA3GLRB | |
| SCHEMBL7173943 | 0.79 | LDHA (1.00) | LDHALDHBALBCYP3A4MAPT | |
| SCHEMBL6846916 | 0.76 | LDHA (0.61) | LDHALDHBALBCYP3A4ACHE | |
| SCHEMBL19203138 | 0.76 | LDHA (0.66) | LDHALDHBALBCYP3A4 | |
| SCHEMBL235873 | 0.75 | LDHA (1.00) | LDHALDHBALBCYP3A4ACHE | |
| SCHEMBL5590144 | 0.73 | LDHA (0.57) | LDHALDHBALBCYP3A4ACHE | |
| SCHEMBL19193997 | 0.73 | LDHA (0.56) | LDHALDHBALBCYP3A4ACHE | |
| SCHEMBL29555202 | 0.72 | ALB (1.00) | LDHALDHBALBCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980350-A4 | HYDROXYNAPHTHOIC ACIDS AND DERIVATIVES | UNIV NEW MEXICO (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6124498-A | Hydroxynaphthoic acids and derivatives | UNIVERSITY OF NEW MEXICO (US) | 2000-09-26 | — | — | US | disclosed |
| EP-0980350-A2 | HYDROXYNAPHTHOIC ACIDS AND DERIVATIVES | The University of New Mexico (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049130-A2 | HYDROXYNAPHTHOIC ACIDS AND DERIVATIVES | THE UNIVERSITY OF NEW MEXICO (US) | 1998-11-05 | — | — | WO | disclosed |