SCHEMBL233361

SCHEMBL233361

CCCc1c(O)c(O)c(C(=O)O)c2cc(Cc3ccccc3)c(C)cc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LDHA P00338 10/20 1.00
LDHB P07195 9/20 1.00
BCL2 P10415 1/20 0.41
BCL2L1 Q07817 1/20 0.41
MCL1 Q07820 1/20 0.41
BCL2A1 Q16548 1/20 0.41
PTPN1 P18031 2/20 0.40
NQO1 P15559 1/20 0.40
PTPN2 P17706 1/20 0.40
PTPN6 P29350 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30417934 1.00 LDHA (1.00) LDHALDHBBCL2BCL2L1MCL1
SCHEMBL7179530 0.93 LDHA (0.87) LDHALDHBBCL2L1
SCHEMBL7187931 0.93 LDHA (0.87) LDHALDHBBCL2BCL2L1MCL1
SCHEMBL15322250 0.90 LDHA (0.82) LDHALDHBBCL2BCL2L1MCL1
SCHEMBL7185727 0.88 LDHA (0.78) LDHALDHBBCL2L1
SCHEMBL235873 0.84 LDHA (1.00) LDHALDHBPTPN1
SCHEMBL7179562 0.83 LDHA (1.00) LDHALDHBBCL2BCL2L1MCL1
SCHEMBL7180813 0.82 LDHA (0.70) LDHALDHB
SCHEMBL2754182 0.81 LDHA (0.71) LDHALDHBPTPN1PTPN2
SCHEMBL7183463 0.80 LDHA (1.00) LDHALDHB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062555-A1 SELENIUM-CONTAINING ANALOGUES OF PHEOMELANIN AND RELATED MATERIALS AND METHODS OF MAKING NORTHWESTERN UNIVERSITY (US) 2026-03-05 US claimed
US-12441890-B2 Selenium-containing analogues of pheomelanin and related materials and methods of making NORTHWESTERN UNIVERSITY (US) 2025-10-14 US claimed
CN-119979222-A Method and device for producing low-freezing diesel oil by taking heavy aromatic hydrocarbon and mixed diesel oil as raw materials 中国石油天然气股份有限公司 2025-05-13 CN claimed
CN-119868545-A Nano system for regulating tumor acidic microenvironment and promoting light immune treatment effect and application thereof 皖南医学院第一附属医院(皖南医学院弋矶山医院) 2025-04-25 CN claimed
US-20250017950-A1 COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS UCL BUSINESS LTD (GB) 2025-01-16 US claimed
CN-119176122-A Reconfigurable distributed driving multi-axis vehicle track tracking method and carrying device 东南大学 2024-12-24 CN claimed
EP-4433077-A1 COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS UCL Business Ltd (GB) 2024-09-25 EP claimed
US-20240000949-A1 Nucleic Acid-Derivatized Therapeutics UNIV CHICAGO (US) 2024-01-04 US claimed
WO-2023235559-A1 SI-SUBSTITUTED LITHIUM THIOBORATE MATERIAL WITH HIGH LITHIUM ION CONDUCTIVITY FOR USE AS SOLID-STATE ELECTROLYTE AND ELECTRODE ADDITIVE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-12-07 WO claimed
US-20230382749-A1 PHOTODRIVEN TRANSFER HYDROGENATION OF N2 TO NH3 CALIFORNIA INST OF TECHN (US) 2023-11-30 US claimed
CN-116367849-A Therapeutic agent derived from nucleic acid 芝加哥大学 2023-06-30 CN claimed
US-20230193039-A1 SELENIUM-CONTAINING ANALOGUES OF PHEOMELANIN AND RELATED MATERIALS AND METHODS OF MAKING NORTHWESTERN UNIVERSITY (US) 2023-06-22 US claimed
WO-2023089313-A1 COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS UCL BUSINESS LTD (GB) 2023-05-25 WO claimed
CN-115753157-A Load simulation device and method for hanger rod of suspension type monorail train 中车南京浦镇车辆有限公司 2023-03-07 CN claimed
CN-115495156-A Independent convolution 3x3 design method based on 4bit to 6bit 北京君正集成电路股份有限公司 2022-12-20 CN claimed
CN-115397972-A In vitro poultry food 优良肉品公司 2022-11-25 CN claimed
US-11408897-B2 Mass defect-based multiplex dimethyl pyrimidinyl ornithine (DiPyrO) tags for high-throughput quantitative proteomics and peptidomics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2022-08-09 US claimed
EP-3983529-A1 IN VITRO AVIAN FOOD PRODUCT Good Meat, Inc. (US) 2022-04-20 EP claimed
WO-2022006387-A9 FULLY AND PARTIALLY BACKBONE-DEGRADABLE POLYMERS VIA LOW TEMPERATURE RING-OPENING METATHESIS POLYMERIZATION (ROMP) NORTHWESTERN UNIVERSITY (US) 2022-04-14 WO claimed
US-20220098674-A1 METHODS AND COMPOSITIONS FOR SELECTING A CANCER TREATMENT IN A SUBJECT SUFFERING FROM CANCER CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - (FR) 2022-03-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230193039-A1 SELENIUM-CONTAINING ANALOGUES OF PHEOMELANIN AND RELATED MATERIALS AND METHODS OF MAKING SELENOI, SCLY, SELP LDHA 3813/4885LDHB 3660/4885BCL2 4409/4885
US-11408897-B2 Mass defect-based multiplex dimethyl pyrimidinyl ornithine (DiPyrO) tags for high-throughput quantitative proteomics and peptidomics PTMS, SRMS, CHAMP1 LDHA 3504/4885LDHB 3305/4885BCL2 4877/4885
US-12441890-B2 Selenium-containing analogues of pheomelanin and related materials and methods of making SELENOI, SCLY, SELP LDHA 3813/4885LDHB 3660/4885BCL2 4409/4885
US-20260062555-A1 SELENIUM-CONTAINING ANALOGUES OF PHEOMELANIN AND RELATED MATERIALS AND METHODS OF MAKING TYR, MPO, SCLY LDHA 3270/4885LDHB 3196/4885BCL2 1956/4885
US-20250017950-A1 COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS POLRMT, TK2, GOT2 LDHA 266/4885LDHB 309/4885BCL2 867/4885
US-20240000949-A1 Nucleic Acid-Derivatized Therapeutics NSUN2, NSUN3, POLRMT LDHA 217/4885LDHB 186/4885BCL2 1497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.