Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13859246 | 0.90 | CA1 (0.31) | CA1CA2RECQLPKM | |
| SCHEMBL13859245 | 0.90 | CA1 (0.31) | CA1CA2RECQLPKM | |
| SCHEMBL16256427 | 0.88 | RECQL (0.32) | CA1CA2NOTUMRECQLPKM | |
| SCHEMBL1304095 | 0.86 | CA1 (0.33) | CA1CA2RECQLPKM | |
| SCHEMBL13859317 | 0.86 | CA1 (0.31) | CA1CA2RECQLPKM | |
| SCHEMBL13859320 | 0.86 | CA1 (0.31) | CA1CA2RECQLPKM | |
| SCHEMBL1611478 | 0.85 | CA1 (0.32) | CA1CA2RECQLPKM | |
| SCHEMBL719548 | 0.85 | RECQL (0.32) | NOTUMRECQLPKM | |
| SCHEMBL1612058 | 0.84 | CA1 (0.33) | CA1CA2RECQLPKM | |
| SCHEMBL112187 | 0.84 | CA1 (0.33) | CA1CA2RECQLPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2360157-B1 | 5-aryl isoxazolines for controlling invertebrate pests | DU PONT (US) | 2012-11-21 | — | — | EP | claimed |
| US-20120053051-A9 | 5-ARYL ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-01 | — | — | US | claimed |
| EP-2360157-A1 | 5-aryl isoxazolines for controlling invertebrate pests | E. I. du Pont de Nemours and Company (US) | 2011-08-24 | — | — | EP | claimed |
| US-20110152081-A1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-06-23 | — | — | US | claimed |
| US-7897630-B2 | 5-aryl isoxazolines for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-01 | — | — | US | claimed |
| US-20090133319-A1 | 5-Aryl Isoxazolines for Controlling Invertebrate Pests | E. I. DU PONT DE NEMOURS AND COMPANY (DE) | 2009-05-28 | — | — | US | claimed |
| US-9073910-B2 | 5-aryl isoxazolines for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-07-07 | — | — | US | disclosed |
| EP-2360157-B1 | 5-aryl isoxazolines for controlling invertebrate pests | DU PONT (US) | 2012-11-21 | — | — | EP | disclosed |
| US-20120053051-A9 | 5-ARYL ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-01 | — | — | US | disclosed |
| EP-2360157-A1 | 5-aryl isoxazolines for controlling invertebrate pests | E. I. du Pont de Nemours and Company (US) | 2011-08-24 | — | — | EP | disclosed |
| US-20110152081-A1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-06-23 | — | — | US | disclosed |
| US-7897630-B2 | 5-aryl isoxazolines for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-01 | — | — | US | disclosed |
| US-20090133319-A1 | 5-Aryl Isoxazolines for Controlling Invertebrate Pests | E. I. DU PONT DE NEMOURS AND COMPANY (DE) | 2009-05-28 | — | — | US | disclosed |
| EP-1966195-A2 | 5-ARYL ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007075459-A2 | 5-ARYL ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053051-A9 | 5-ARYL ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | PRXL2A, C5, CBR3 | CA1 2026/4885CA2 992/4885NOTUM 2550/4885 |
| US-20090133319-A1 | 5-Aryl Isoxazolines for Controlling Invertebrate Pests | PRXL2A, C5, CBR3 | CA1 2100/4885CA2 1003/4885NOTUM 2858/4885 |
| US-20110152081-A1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | PRXL2A, C5, CBR3 | CA1 2026/4885CA2 992/4885NOTUM 2550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.