Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1612058 | 0.88 | CA1 (0.33) | CA1CA2RECQLKDM4EMAPT | |
| SCHEMBL13859317 | 0.88 | CA1 (0.31) | CA1CA2RECQLPKM | |
| SCHEMBL1304095 | 0.88 | CA1 (0.33) | CA1CA2RECQLKDM4EMAPT | |
| SCHEMBL13859320 | 0.88 | CA1 (0.31) | CA1CA2RECQLPKM | |
| SCHEMBL112195 | 0.88 | CA1 (0.32) | CA1CA2RECQLPKM | |
| SCHEMBL1610490 | 0.88 | NISCH (0.37) | CA1CA2RECQLKDM4EMAPT | |
| SCHEMBL1609370 | 0.87 | PDE3B (0.33) | — | |
| SCHEMBL588568 | 0.86 | RECQL (0.36) | CA1CA2RECQLPKM | |
| SCHEMBL30021375 | 0.86 | CA1 (0.30) | CA1CA2 | |
| SCHEMBL3116717 | 0.86 | RECQL (0.32) | CA1CA2RECQLKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2176244-B1 | Method for preparing 5-haloalkyl-4,5-dihydroisoxazole derivatives | DU PONT (US) | 2016-06-01 | — | — | EP | disclosed |
| US-8513431-B2 | Method for preparing 5-haloalkyl-4, 5-dihydroisoxazole derivatives | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-08-20 | — | — | US | disclosed |
| US-20130165663-A9 | METHOD FOR PREPARING 5-HALOALKYL-4, 5-DIHYDROISOXAZOLE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-27 | — | — | US | disclosed |
| EP-2069338-B1 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2012-11-28 | — | — | EP | disclosed |
| US-20120277442-A1 | METHOD FOR PREPARING 5-HALOALKYL-4, 5-DIHYDROISOXAZOLE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-01 | — | — | US | disclosed |
| US-8217180-B2 | Method for preparing 5-haloalkyl-4,5-dihydroisoxazole derivatives | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-07-10 | — | — | US | disclosed |
| EP-2332937-A1 | Insecticidal isoxazolines | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| EP-2330106-A1 | Insecticidal isoxazolines | Bayer CropScience AG (DE) | 2011-06-08 | — | — | EP | disclosed |
| US-20110086886-A2 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2011-04-14 | — | — | US | disclosed |
| US-20100249424-A1 | METHOD FOR PREPARING 5-HALOALKYL-4,5-DIHYDROISOXAZOLE DERIVATIVES | E.I.DUPONT DE NEMOURS AND COMPANY (US) | 2010-09-30 | — | — | US | disclosed |
| US-20100249191-A1 | N-Methyl benzamide derivatives | BAYER CROPSCIENCE SA (FR) | 2010-09-30 | — | — | US | disclosed |
| EP-2176244-A2 | METHOD FOR PREPARING 5-HALOALKYL-4,5-DIHYDROISOXAZOLE DERIVATIVES | E. I. du Pont de Nemours and Company (US) | 2010-04-21 | — | — | EP | disclosed |
| EP-2069338-A1 | INSECTICIDAL ISOXAZOLINES | Bayer CropScience AG (DE) | 2009-06-17 | — | — | EP | disclosed |
| WO-2009025983-A2 | METHOD FOR PREPARING 5-HALOALKYL-4,5-DIHYDROISOXAZOLE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-02-26 | — | — | WO | disclosed |
| WO-2008019760-A1 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165663-A9 | METHOD FOR PREPARING 5-HALOALKYL-4, 5-DIHYDROISOXAZOLE DERIVATIVES | PRDX2, PRXL2A, PRDX1 | CA1 1133/4885CA2 583/4885RECQL 321/4885 |
| US-20100249424-A1 | METHOD FOR PREPARING 5-HALOALKYL-4,5-DIHYDROISOXAZOLE DERIVATIVES | PRDX2, PRXL2A, PRDX1 | CA1 1133/4885CA2 583/4885RECQL 321/4885 |
| US-20110086886-A2 | INSECTICIDAL ISOXAZOLINES | HAX1, INA, CYCS | CA1 2787/4885CA2 1239/4885RECQL 1874/4885 |
| US-20100249191-A1 | N-Methyl benzamide derivatives | GNMT, SCN1A, INA | CA1 3662/4885CA2 1117/4885RECQL 2673/4885 |
| US-20120277442-A1 | METHOD FOR PREPARING 5-HALOALKYL-4, 5-DIHYDROISOXAZOLE DERIVATIVES | PRDX2, PRXL2A, PRDX1 | CA1 1133/4885CA2 583/4885RECQL 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.