SCHEMBL13859320

SCHEMBL13859320

FC(F)(F)C1(c2cc(Cl)cc(Cl)c2)CC(c2ccc(S)c(Br)c2)=NO1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
RECQL P46063 1/20 0.31
PKM P14618 1/20 0.30
PDE3B Q13370 1/20 0.30
PDE3A Q14432 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13859317 1.00 CA1 (0.31) CA1CA2RECQLPKMPDE3B
SCHEMBL112195 0.88 CA1 (0.32) CA1CA2RECQLPKMPDE3B
SCHEMBL1611478 0.88 CA1 (0.32) CA1CA2RECQLPKM
SCHEMBL1612058 0.86 CA1 (0.33) CA1CA2RECQLPKM
SCHEMBL1304095 0.86 CA1 (0.33) CA1CA2RECQLPKMPDE3B
SCHEMBL717972 0.86 CA1 (0.32) CA1CA2RECQLPKM
SCHEMBL588568 0.84 RECQL (0.36) CA1CA2RECQLPKM
SCHEMBL30021375 0.84 CA1 (0.30) CA1CA2
SCHEMBL3116717 0.84 RECQL (0.32) CA1CA2RECQLPKM
SCHEMBL1305787 0.84 CA1 (0.30) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2709983-B1 INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2018-04-18 EP disclosed
EP-2922831-B1 PESTICIDAL COMPOUNDS BASED ON ARYLTHIOSULFONAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2017-10-18 EP disclosed
EP-2922831-B1 PESTICIDAL COMPOUNDS BASED ON ARYLTHIOSULFONAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2017-10-18 EP disclosed
US-9686988-B2 Pesticidal compounds based on arylthiosulfonamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2017-06-27 US disclosed
US-9686988-B2 Pesticidal compounds based on arylthiosulfonamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2017-06-27 US disclosed
US-9686988-B2 Pesticidal compounds based on arylthiosulfonamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2017-06-27 US disclosed
US-9675073-B2 Insecticidal compounds based on N-arylsulfanylmethylcarboxamidearylthiosulfonamides derivatives SYNGENTA PARTICIPATIONS AG (CH) 2017-06-13 US disclosed
US-9675073-B2 Insecticidal compounds based on N-arylsulfanylmethylcarboxamidearylthiosulfonamides derivatives SYNGENTA PARTICIPATIONS AG (CH) 2017-06-13 US disclosed
US-9675073-B2 Insecticidal compounds based on N-arylsulfanylmethylcarboxamidearylthiosulfonamides derivatives SYNGENTA PARTICIPATIONS AG (CH) 2017-06-13 US disclosed
US-20160286808-A1 PESTICIDAL COMPOUNDS BASED ON ARYLTHIOSULFONAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2016-10-06 US disclosed
EP-2922837-A1 INSECTICIDAL COMPOUNDS BASED ON N-(ARYLSULFANYLMETHYL) CARBOXAMIDE DERIVATIVES Syngenta Participations AG (CH) 2015-09-30 EP disclosed
EP-2922831-A1 PESTICIDAL COMPOUNDS BASED ON ARYLTHIOSULFONAMIDE DERIVATIVES Syngenta Participations AG (CH) 2015-09-30 EP disclosed
US-8895587-B2 Insecticidal compounds based on arylthioacetamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2014-11-25 US disclosed
WO-2014079937-A1 PESTICIDAL COMPOUNDS BASED ON ARYLTHIOSULFONAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2014-05-30 WO disclosed
WO-2014079937-A1 PESTICIDAL COMPOUNDS BASED ON ARYLTHIOSULFONAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2014-05-30 WO disclosed
WO-2014079941-A1 INSECTICIDAL COMPOUNDS BASED ON N-(ARYLSULFANYLMETHYL) CARBOXAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2014-05-30 WO disclosed
WO-2014079941-A1 INSECTICIDAL COMPOUNDS BASED ON N-(ARYLSULFANYLMETHYL) CARBOXAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2014-05-30 WO disclosed
US-20140107161-A1 INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2014-04-17 US disclosed
EP-2709983-A1 INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES Syngenta Participations AG (CH) 2014-03-26 EP disclosed
WO-2012156400-A1 INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2012-11-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160286808-A1 PESTICIDAL COMPOUNDS BASED ON ARYLTHIOSULFONAMIDE DERIVATIVES ACHE, CHRM2, DDT CA1 2938/4885CA2 636/4885RECQL 508/4885
US-20140107161-A1 INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES NAT1, ACHE, CHRM1 CA1 2681/4885CA2 822/4885RECQL 666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.