P-Xylene

P-Xylene

SCHEMBL7180224

CCc1ccc(C=O)cc1.Cc1ccc(C)cc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.70
ALDH1A1 P00352 5/20 0.59
MAPT P10636 2/20 0.59
LMNA P02545 1/20 0.59
HPGD P15428 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
ALDH3A1 P30838 1/20 0.47
ALDH1A3 P47895 1/20 0.47
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
KDM4E B2RXH2 1/20 0.43
ALOX5 P09917 1/20 0.43
PTGS1 P23219 1/20 0.43
PTGS2 P35354 1/20 0.43
HCRTR2 O43614 1/20 0.41
IGF1R P08069 1/20 0.41
PIM1 P11309 1/20 0.41
PIM2 Q9P1W9 1/20 0.41
TYR P14679 1/20 0.40
CYP2A13 Q16696 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL154747 0.91 ALDH1A1 (0.68) CYP2A6ALDH1A1MAPTLMNAHPGD
Ammonia Solution, Strong SCHEMBL29186824 0.89 ALDH1A1 (0.66) CYP2A6ALDH1A1MAPTLMNAHPGD
SCHEMBL20546774 0.86 CYP2A6 (0.76) CYP2A6ALDH1A1MAPTLMNAHPGD
SCHEMBL2121124 0.84 ALDH1A1 (0.61) CYP2A6ALDH1A1MAPTLMNAHPGD
SCHEMBL29174340 0.84 ALDH1A1 (0.61) CYP2A6ALDH1A1MAPTLMNAHPGD
SCHEMBL29171 0.83
SCHEMBL8469408 0.83 CYP2A6 (1.00) CYP2A6ALDH1A1SMN1; SMN2ALDH3A1ALDH1A3
P-Xylene SCHEMBL10939332 0.83 CYP2A6 (1.00) CYP2A6ALDH1A1SMN1; SMN2ALDH3A1ALDH1A3
Formamide SCHEMBL10900997 0.82 CA2 (0.45) CYP2A6ALDH1A1MAPTLMNAHPGD
SCHEMBL6546965 0.82 PTGS1 (0.60) CYP2A6SMN1; SMN2ALOX5PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6562996-B2 Alkyl aromatic aldehydes EXXONMOBIL CHEMICAL PATENTS INC. 2003-05-13 US disclosed
WO-2003016252-A2 ALKYL AROMATIC ALDEHYDES EXXONMOBIL CHEMICAL PATENTS INC. (US) 2003-02-27 WO disclosed
US-20020068841-A1 Alkyl aromatic aldehydes EXXONMOBIL CHEMICAL PATENTS INC. 2002-06-06 US disclosed