Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22468531 | 0.84 | ALDH1A1 (0.35) | L3MBTL1MAPK1MAPTSMN1; SMN2GAA | |
| SCHEMBL7184437 | 0.83 | MAPT (0.45) | L3MBTL1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL7183006 | 0.81 | CFTR (0.45) | L3MBTL1MAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7192206 | 0.80 | KMT2A (0.52) | MAPK1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7191686 | 0.79 | L3MBTL1 (0.45) | L3MBTL1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL16564262 | 0.74 | L3MBTL1 (0.53) | L3MBTL1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL22468521 | 0.74 | L3MBTL1 (0.34) | L3MBTL1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL117981 | 0.74 | FGFR4 (0.51) | L3MBTL1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL31315323 | 0.74 | FGFR4 (0.51) | L3MBTL1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL9952081 | 0.73 | MAPT (0.54) | L3MBTL1MAPK1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6582351-B1 | Benzimidazole heterocyclic compounds having pharmacological activities, and their use as a medicament for treatment or prevention of diseases mediated by cGMP-PDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-24 | — | — | US | disclosed |