Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21272824 | 0.74 | ADORA3 (0.51) | ADORA3ALDH1A1SMN1; SMN2PDPK1CA12 | |
| SCHEMBL19208631 | 0.71 | ADORA3 (0.51) | ADORA3ALDH1A1SMN1; SMN2PDPK1CA12 | |
| SCHEMBL7468020 | 0.70 | ADORA3 (0.66) | ADORA3ALDH1A1SMN1; SMN2PDPK1CA12 | |
| SCHEMBL5799684 | 0.69 | ADORA3 (1.00) | ADORA3ALDH1A1SMN1; SMN2PDPK1CA12 | |
| SCHEMBL364844 | 0.69 | ADORA3 (0.50) | ADORA3KDM4EHSD17B10HPGDRAB9A | |
| SCHEMBL28900827 | 0.67 | ALDH1A1 (0.42) | ALDH1A1MEN1PKMKMT2ACREBBP | |
| SCHEMBL7422510 | 0.67 | ADORA3 (0.48) | ADORA3ALDH1A1SMN1; SMN2PDPK1CA12 | |
| SCHEMBL7419559 | 0.67 | ADORA3 (0.48) | ADORA3ALDH1A1SMN1; SMN2PDPK1CA12 | |
| SCHEMBL30118407 | 0.66 | DDB1 (0.48) | ALDH1A1MEN1PKMKMT2ACREBBP | |
| SCHEMBL7062655 | 0.66 | ADORA3 (0.55) | ADORA3ALDH1A1SMN1; SMN2PDPK1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296687-A2 | TREATMENT OF MALE SEXUAL DYSFUNCTION | Pfizer Limited (GB) | 2003-04-02 | — | — | EP | claimed |
| WO-2002003995-A2 | TREATMENT OF MALE SEXUAL DYSFUNCTION | PFIZER LIMITED (GB) | 2002-01-17 | — | — | WO | claimed |
| EP-0977756-A1 | PYRAZOLOPYRIMIDINONES WHICH INHIBIT TYPE 5 CYCLIC GUANOSINE 3',5'-MONOPHOSPHATE PHOSPHODIESTERASE (cGMP PDE5) FOR THE TREATMENT OF SEXUAL DYSFUNCTION | Pfizer Limited (GB) | 2000-02-09 | — | — | EP | claimed |
| WO-1998049166-A1 | PYRAZOLOPYRIMIDINONES WHICH INHIBIT TYPE 5 CYCLIC GUANOSINE 3',5'-MONOPHOSPHATE PHOSPHODIESTERASE (cGMP PDE5) FOR THE TREATMENT OF SEXUAL DYSFUNCTION | PFIZER LIMITED (GB) | 1998-11-05 | — | — | WO | claimed |
| WO-2013067309-A1 | METHODS AND COMPOSITIONS FOR ORAL ADMINISTRATION OF MELANOCORTIN RECEPTOR AGONIST COMPOUNDS | XION PHARMACEUTICAL CORPORATION (US) | 2013-05-10 | — | — | WO | disclosed |
| EP-1140044-A2 | cGMP PDE 5 INHIBITORS FOR INHALATION IN THE TREATMENT OF SEXUAL DYSFUNCTION | Novartis AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037061-A2 | cGMP PDE 5 INHIBITORS FOR INHALATION IN THE TREATMENT OF SEXUAL DYSFUNCTION | NOVARTIS AG (CH) | 2000-06-29 | — | — | WO | disclosed |