Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.30 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135552 | 0.93 | TSHR (0.46) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL28438742 | 0.93 | TSHR (0.46) | TSHRLMNATHRBALDH1A1TDP1 | |
| Iodide SCHEMBL6657020 | 0.89 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL863480 | 0.89 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Ammonia Solution, Strong SCHEMBL28759713 | 0.89 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Water SCHEMBL3700992 | 0.89 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL336735 | 0.89 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL2139803 | 0.89 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL3577655 | 0.89 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Iodide SCHEMBL27498959 | 0.89 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915753-B1 | SILOXANE-MODIFIED ADHESIVE/ADHEREND SYSTEMS | AMERON INT CORP (US) | 2003-01-29 | — | — | EP | disclosed |
| EP-0915753-A4 | SILOXANE-MODIFIED ADHESIVE/ADHEREND SYSTEMS | AMERON INT CORP (US) | 2001-04-25 | — | — | EP | disclosed |
| US-5942073-A | PREPARED BY COMBINING AN EPOXY RESIN WITH AN ORGANOSILANE INGREDIENT, A POLYSILOXANE RESIN, AN AMINE HARDENER, AN ORGANOMETALLIC CATALYST, A BASE CATALYST, AND ANY THICKENER AND EXTENDER PIGMENT; ROOM TEMPERATURE CURING | AMERON INTERNATIONAL CORPORATION (US) | 1999-08-24 | — | — | US | disclosed |
| EP-0915753-A1 | SILOXANE-MODIFIED ADHESIVE/ADHEREND SYSTEMS | AMERON INTERNATIONAL CORPORATION (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997042027-A1 | SILOXANE-MODIFIED ADHESIVE/ADHEREND SYSTEMS | AMERON INTERNATIONAL CORPORATION (US) | 1997-11-13 | — | — | WO | disclosed |