Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | RORC | P51449 | 5/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | PARG | Q86W56 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6517292 | 0.91 | MAPT (0.59) | PPARGRORCPARGHDAC1MMP13 | |
| SCHEMBL6472829 | 0.90 | MAPT (0.57) | PPARGRORCCA2PARGMMP13 | |
| SCHEMBL7095851 | 0.89 | MMP13 (0.65) | PPARGRORCPARGHDAC1MMP13 | |
| SCHEMBL7100567 | 0.88 | MMP13 (0.56) | PPARGRORCPARGHDAC1MMP13 | |
| SCHEMBL6532934 | 0.86 | PPARG (0.56) | PPARGRORCPARGHDAC1MMP13 | |
| SCHEMBL7101956 | 0.85 | MMP13 (0.54) | PPARGRORCPARGHDAC1MMP13 | |
| SCHEMBL6246256 | 0.85 | MAPT (0.58) | PPARGHDAC1MMP13SLC22A8KDM4E | |
| SCHEMBL7097679 | 0.84 | MMP13 (0.60) | PPARGRORCPARGHDAC1MMP13 | |
| SCHEMBL7102887 | 0.83 | MMP13 (0.54) | PPARGHDAC1MMP13SLC22A8KDM4E | |
| SCHEMBL7102983 | 0.83 | MMP13 (0.54) | PPARGHDAC1MMP13SLC22A8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | ANDRIANJARA CHARLES (FR) | 2002-12-19 | — | — | US | claimed |
| EP-1368324-A1 | QUINAZOLINES AS MMP-13 INHIBITORS | Warner-Lambert Company LLC (US) | 2003-12-10 | — | — | EP | disclosed |
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | ANDRIANJARA CHARLES (FR) | 2002-12-19 | — | — | US | disclosed |
| WO-2002064572-A1 | QUINAZOLINES AS MMP-13 INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | MMP13, MMP9, MMP3 | PPARG 3301/4885RORC 1297/4885CA2 272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.