Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459648 | 0.84 | CYP2C19 (0.40) | CYP2C19SMN1; SMN2KDM4EALDH1A1TDP1 | |
| SCHEMBL7187920 | 0.81 | CYP2C19 (0.38) | CYP2C19SMN1; SMN2KDM4EALDH1A1TDP1 | |
| SCHEMBL9786071 | 0.79 | HSD17B10 (0.54) | SMN1; SMN2MAPK1LMNAKDM4EALDH1A1 | |
| SCHEMBL1699372 | 0.76 | HPGD (0.52) | SMN1; SMN2ALDH1A1L3MBTL1HPGDHTT | |
| SCHEMBL13067434 | 0.72 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPK1LMNAKDM4EALDH1A1 | |
| SCHEMBL20147971 | 0.71 | PDCD1 (0.46) | SMN1; SMN2MAPK1LMNAKDM4EALDH1A1 | |
| SCHEMBL8357110 | 0.70 | KDM4E (0.47) | CYP2C19SMN1; SMN2KDM4EALDH1A1TDP1 | |
| SCHEMBL28150234 | 0.70 | KDM4E (0.49) | CYP2C19SMN1; SMN2KDM4EALDH1A1TDP1 | |
| SCHEMBL28747724 | 0.70 | ALOX15 (0.65) | LMNAKDM4EALDH1A1TDP1GAA | |
| SCHEMBL5146259 | 0.69 | HSD17B10 (0.54) | SMN1; SMN2MAPK1LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980350-A4 | HYDROXYNAPHTHOIC ACIDS AND DERIVATIVES | UNIV NEW MEXICO (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6124498-A | Hydroxynaphthoic acids and derivatives | UNIVERSITY OF NEW MEXICO (US) | 2000-09-26 | — | — | US | disclosed |
| EP-0980350-A2 | HYDROXYNAPHTHOIC ACIDS AND DERIVATIVES | The University of New Mexico (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049130-A2 | HYDROXYNAPHTHOIC ACIDS AND DERIVATIVES | THE UNIVERSITY OF NEW MEXICO (US) | 1998-11-05 | — | — | WO | disclosed |