Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4944820 | 0.89 | HSD17B10 (0.57) | HSD17B10TAAR1GAANPSR1MEN1 | |
| SCHEMBL9786071 | 0.86 | HSD17B10 (0.54) | HSD17B10TAAR1GAANPSR1MEN1 | |
| SCHEMBL151820 | 0.86 | HSD17B10 (0.57) | HSD17B10TAAR1GAANPSR1MEN1 | |
| SCHEMBL30969123 | 0.86 | HSD17B10 (0.57) | HSD17B10TAAR1GAANPSR1MEN1 | |
| SCHEMBL31357219 | 0.84 | SMN1; SMN2 (0.47) | HSD17B10GAAKDM4EALDH1A1IMPDH2 | |
| SCHEMBL28608032 | 0.83 | TAAR1 (0.43) | HSD17B10TAAR1MEN1KMT2AKDM4E | |
| SCHEMBL11330327 | 0.81 | IMPDH2 (0.60) | HSD17B10GAANPSR1MEN1KMT2A | |
| SCHEMBL13067439 | 0.80 | MEN1 (0.49) | TAAR1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL12904375 | 0.79 | HSD17B10 (0.54) | HSD17B10GAANPSR1KDM4EALDH1A1 | |
| SCHEMBL12904374 | 0.79 | HSD17B10 (0.50) | HSD17B10GAANPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208086-A1 | UBIQUINONE ANALOGS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-09-06 | — | — | US | disclosed |
| US-20070203080-A1 | New Drug Delivery System for Crossing the Blood Brain Barrier | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-30 | — | — | US | disclosed |
| WO-2007095630-A2 | NEW UBIQUINONE ANALOGS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-23 | — | — | WO | disclosed |
| WO-2007095631-A2 | NEW DRUG DELIVERY SYSTEM FOR CROSSING THE BLOOD BRAIN BARRIER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208086-A1 | UBIQUINONE ANALOGS AND METHODS OF USE | NDUFB7, NDUFB1, NDUFB3 | HSD17B10 209/4885TAAR1 4636/4885GAA 917/4885 |
| US-20070203080-A1 | New Drug Delivery System for Crossing the Blood Brain Barrier | NDUFB5, NDUFB7, NDUFB3 | HSD17B10 254/4885TAAR1 4330/4885GAA 1514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.