Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL595537 | 0.94 | TP53 (0.52) | ALDH1A1TSHRCALM1TP53TDP1 | |
| SCHEMBL595507 | 0.90 | TP53 (0.45) | ALDH1A1TSHRCALM1TP53TDP1 | |
| Diphenylmethane SCHEMBL10934952 | 0.87 | ALDH1A1 (0.70) | ALDH1A1TSHRCALM1TP53TDP1 | |
| SCHEMBL22542506 | 0.85 | CYP17A1 (0.42) | TP53TDP1LTA4HLOXL2 | |
| SCHEMBL10616284 | 0.83 | ALDH1A1 (0.52) | ALDH1A1TSHRTP53TDP1FAAH | |
| Styrene SCHEMBL9657977 | 0.81 | TP53 (0.60) | ALDH1A1TSHRTP53TDP1MAOA | |
| SCHEMBL8441622 | 0.81 | TEAD4 (0.47) | ALDH1A1TSHRCALM1IDH1HNF4A | |
| SCHEMBL417837 | 0.81 | MAOA (0.58) | ALDH1A1CALM1ELANEIDH1PRSS1 | |
| SCHEMBL595016 | 0.80 | TP53 (0.52) | ALDH1A1TSHRTP53TDP1FAAH | |
| SCHEMBL29375309 | 0.80 | TP53 (0.52) | ALDH1A1TSHRTP53TDP1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140275337-A1 | CONTINUOUS PROCESSING OF ASPHALT FORMULATIONS | BUILDING MATERIALS INVESTMENT CORPORATION (US) | 2014-09-18 | — | — | US | claimed |
| EP-0283038-B1 | (VINYLPHENYL)PHENYLMETHANE AND METHOD FOR PRODUCING (BENZOYLPHENYL)PROPIONIC ACID | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1991-06-12 | — | — | EP | claimed |
| US-4922052-A | (Vinylphenyl)phenylmethane and method for producing (benzoylphenyl) propionic acid | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-05-01 | — | — | US | claimed |
| EP-0283038-A1 | (Vinylphenyl)phenylmethane and method for producing (benzoylphenyl)propionic acid | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1988-09-21 | — | — | EP | claimed |
| JP-63230653-A | — | — | None | — | — | JP | disclosed |
| JP-63230652-A | — | — | None | — | — | JP | disclosed |
| JP-63230647-A | — | — | None | — | — | JP | disclosed |
| US-20250257027-A1 | SECOND GENERATION GRP94-SELECTIVE INHIBITORS | UNIVERSITY OF KANSAS (US) | 2025-08-14 | — | — | US | disclosed |
| US-12269798-B2 | Second generation GRP94-selective inhibitors | UNIVERSITY OF KANSAS (US) | 2025-04-08 | — | — | US | disclosed |
| US-20210300872-A1 | SECOND GENERATION GRP94-SELECTIVE INHIBITORS | UNIVERSITY OF KANSAS | 2021-09-30 | — | — | US | disclosed |
| US-11028041-B2 | Second generation GRP94-selective inhibitors | UNIVERSITY OF KANSAS (US) | 2021-06-08 | — | — | US | disclosed |
| US-20200190017-A1 | SECOND GENERATION GRP94-SELECTIVE INHIBITORS | UNIVERSITY OF KANSAS | 2020-06-18 | — | — | US | disclosed |
| EP-0283038-A1 | (Vinylphenyl)phenylmethane and method for producing (benzoylphenyl)propionic acid | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1988-09-21 | — | — | EP | disclosed |
| EP-0283038-A1 | (Vinylphenyl)phenylmethane and method for producing (benzoylphenyl)propionic acid | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1988-09-21 | — | — | EP | disclosed |
| US-4743497-A | ASPHALT, ALKADIENE-VINYLARENE COPOLYMER, HYDROCARBON RESIN | PHILLIPS PETROLEUM COMPANY (US) | 1988-05-10 | — | — | US | disclosed |
| US-4479837-A | Filament rein for cement impregnated with resin of thickenable composition based on an adduct of alkadiene polymers and acid anhydride | PHILLIPS PETROLEUM COMPANY (US) | 1984-10-30 | — | — | US | disclosed |
| US-4430465-A | ALKADIENE-VINYLARENE COPOLYMER, PETROLEUM RESIN, BRANCHED AMINE, ANTISTRIPPING, FIBERS, MATS, COATINGS | PHILLIPS PETROLEUM COMPANY (US) | 1984-02-07 | — | — | US | disclosed |
| US-4423177-A | WITH THICKENERS AND PEROXIDE | PHILLIPS PETROLEUM COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| US-4414340-A | WITH REDUCED BLISTERING, POLYALKADIENE, PEROXIDE, POLYOFEFIN, FILLER, RELEASE AGENT, MOLDING | PHILLIPS PETROLEUM COMPANY (US) | 1983-11-08 | — | — | US | disclosed |
| US-4371635-A | MOLDING MATERIALS; FLEXIBILITY; HARDNESS; TENSILE STRENGTH | PHILLIPS PETROLEUM COMPANY (US) | 1983-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12269798-B2 | Second generation GRP94-selective inhibitors | HSP90B1, HSP90AB2P, HSPE1 | ALDH1A1 3322/4885TSHR 2005/4885CALM1 2173/4885 |
| US-20210300872-A1 | SECOND GENERATION GRP94-SELECTIVE INHIBITORS | HSP90B1, HSP90AB2P, HSPE1 | ALDH1A1 3322/4885TSHR 2005/4885CALM1 2173/4885 |
| US-20250257027-A1 | SECOND GENERATION GRP94-SELECTIVE INHIBITORS | HSP90B1, HSP90AB2P, HSPE1 | ALDH1A1 3289/4885TSHR 1925/4885CALM1 2110/4885 |
| US-11028041-B2 | Second generation GRP94-selective inhibitors | HSP90B1, HSP90AB2P, HSPE1 | ALDH1A1 3289/4885TSHR 1925/4885CALM1 2110/4885 |
| US-20200190017-A1 | SECOND GENERATION GRP94-SELECTIVE INHIBITORS | HSP90B1, HSP90AB2P, HSPE1 | ALDH1A1 3289/4885TSHR 1925/4885CALM1 2110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.