Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLLT1 | Q03111 | 4/20 | 0.40 |
| ▸ | MLLT3 | P42568 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7132559 | 1.00 | MLLT1 (0.40) | MLLT1MLLT3ALDH1A1L3MBTL1CHRNB2 | |
| SCHEMBL7129660 | 0.90 | CHRNA7 (0.38) | ALDH1A1CHRNB2CHRNA4PTPN1CHRNA7 | |
| SCHEMBL7117473 | 0.89 | FLT3 (0.37) | ALDH1A1L3MBTL1CHRNB2CHRNA4PTPN1 | |
| SCHEMBL7124994 | 0.89 | PTPN1 (0.35) | ALDH1A1L3MBTL1CHRNB2CHRNA4PTPN1 | |
| SCHEMBL7123200 | 0.89 | L3MBTL3 (0.37) | ALDH1A1L3MBTL1CHRNB2CHRNA4PTPN1 | |
| SCHEMBL7590680 | 0.89 | CHRNB2 (0.40) | ALDH1A1CHRNB2CHRNA4PTPN1CHRNA7 | |
| SCHEMBL7597918 | 0.89 | L3MBTL3 (0.37) | ALDH1A1L3MBTL1CHRNB2CHRNA4PTPN1 | |
| SCHEMBL7121913 | 0.89 | CHRNB2 (0.40) | ALDH1A1CHRNB2CHRNA4PTPN1CHRNA7 | |
| SCHEMBL7225384 | 0.89 | CHRNB2 (0.40) | ALDH1A1CHRNB2CHRNA4CHRNA7CHRM3 | |
| SCHEMBL7130837 | 0.88 | PTPN1 (0.44) | ALDH1A1L3MBTL1CHRNB2CHRNA4PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311505-A2 | QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE ( NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS ) | PHARMACIA & UPJOHN COMPANY (US) | 2003-05-21 | — | — | EP | claimed |
| WO-2002016355-A2 | QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC) ACETYLCHOLINE RECEPTOR LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-28 | — | — | WO | claimed |