Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10451653 | 0.89 | THRB (0.53) | THRBTHRAHCAR2TSHRALDH1A1 | |
| SCHEMBL29577996 | 0.89 | THRB (0.53) | THRBTHRAHCAR2TSHRALDH1A1 | |
| SCHEMBL960201 | 0.82 | IDO1 (0.48) | THRBTHRAHCAR2TSHRALDH1A1 | |
| SCHEMBL1371361 | 0.82 | THRB (0.47) | THRBTHRAHCAR2TSHRALDH1A1 | |
| SCHEMBL9555275 | 0.82 | THRB (0.47) | THRBTHRAHCAR2TSHRALDH1A1 | |
| SCHEMBL2029842 | 0.81 | THRB (0.46) | THRBTHRAHCAR2TSHRALDH1A1 | |
| SCHEMBL961210 | 0.81 | L3MBTL1 (0.50) | THRBALDH1A1 | |
| SCHEMBL21913950 | 0.81 | THRB (0.46) | THRBTHRAHCAR2TSHRALDH1A1 | |
| SCHEMBL1591973 | 0.81 | MAOB (0.46) | THRBTHRATSHRALDH1A1LMNA | |
| SCHEMBL33527978 | 0.81 | THRB (0.46) | THRBTHRAHCAR2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1279720-A1 | FLAME RETARDANT, FLAME-RETARDANT RESIN COMPOSITION, MOLDED OBJECT, AND ELECTRONIC PART | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 2003-01-29 | — | — | EP | disclosed |