SCHEMBL33527978

SCHEMBL33527978

C=COCc1ccccc1COC(=O)C=C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.46
THRA P10827 1/20 0.39
HCAR2 Q8TDS4 1/20 0.38
TSHR P16473 6/20 0.37
ALDH1A1 P00352 4/20 0.37
TP53 P04637 3/20 0.37
HIF1A Q16665 3/20 0.37
CYP3A4 P08684 3/20 0.37
HSD17B10 Q99714 1/20 0.37
LMNA P02545 1/20 0.36
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HPGD P15428 1/20 0.34
PPARG P37231 1/20 0.34
AKT1 P31749 1/20 0.33
CA12 O43570 1/20 0.33
AKR1B10 O60218 1/20 0.33
AKR1B1 P15121 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29577996 0.91 THRB (0.53) THRBTHRAHCAR2TSHRALDH1A1
SCHEMBL10451653 0.91 THRB (0.53) THRBTHRAHCAR2TSHRALDH1A1
SCHEMBL1371361 0.84 THRB (0.47) THRBTHRAHCAR2TSHRALDH1A1
SCHEMBL11201688 0.83 THRB (0.50) THRBTHRAHCAR2TSHRALDH1A1
SCHEMBL27767979 0.83 SMN1; SMN2 (0.50) THRBTHRAHCAR2TSHRALDH1A1
SCHEMBL8602403 0.81 IDO1 (0.38) TSHRALDH1A1LMNASMN1; SMN2
SCHEMBL29728038 0.81 IDO1 (0.38) TSHRALDH1A1LMNASMN1; SMN2
SCHEMBL7181027 0.81 THRB (0.47) THRBTHRAHCAR2TSHRALDH1A1
SCHEMBL960201 0.81 IDO1 (0.48) THRBTHRAHCAR2TSHRALDH1A1
SCHEMBL9555275 0.81 THRB (0.47) THRBTHRAHCAR2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092188-A1 Radiation Curable Ink Composition For Ink Jet And Ink Jet Recording Method SEIKO EPSON CORP (JP) 2026-04-02 US disclosed
US-20260092190-A1 Radiation Curable Ink Composition For Ink Jet And Recording Apparatus SEIKO EPSON CORP (JP) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092190-A1 Radiation Curable Ink Composition For Ink Jet And Recording Apparatus KAT8, TAS2R8, NLRP3 THRB 1617/4885THRA 1661/4885HCAR2 3153/4885
US-20260092188-A1 Radiation Curable Ink Composition For Ink Jet And Ink Jet Recording Method JAK1, EED, PI4KA THRB 2350/4885THRA 2584/4885HCAR2 2420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.