SCHEMBL7181065

SCHEMBL7181065

Fc1cccc(Cl)c1C(Cl)Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.44
ALDH1A1 P00352 1/20 0.44
TAAR1 Q96RJ0 1/20 0.42
HTT P42858 2/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2A6 P11509 1/20 0.36
ATM Q13315 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
SMARCA2 P51531 2/20 0.35
SMARCA4 P51532 2/20 0.35
PBRM1 Q86U86 2/20 0.35
GLA P06280 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11090617 0.82 GAA (0.41) GAAALDH1A1TAAR1HTTMEN1
SCHEMBL5368610 0.82 CYP1A2 (0.45) ALDH1A1TAAR1MEN1KMT2ACYP1A2
SCHEMBL17138366 0.81 GAA (0.44) GAAALDH1A1TAAR1HTTCES2
SCHEMBL4547923 0.79 ALDH1A1 (0.42) GAAALDH1A1TAAR1HTTMEN1
SCHEMBL20256641 0.79 TAAR1 (0.45) GAAALDH1A1TAAR1HTTKMT2A
SCHEMBL1397081 0.77 ALDH1A1 (0.41) GAAALDH1A1TAAR1HTTMEN1
SCHEMBL22993866 0.76 ALDH1A1 (0.41) GAAALDH1A1TAAR1HTTCES2
SCHEMBL5826055 0.76 CES2 (0.33) GAAALDH1A1TAAR1CES2CES1
SCHEMBL31521541 0.76 CYP1A2 (0.48) GAAALDH1A1TAAR1HTTCYP1A2
SCHEMBL23212814 0.76 CES2 (0.41) GAAALDH1A1TAAR1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178100-B Dechlorination reduction method for 2-chloro-6-fluorotrichlorobenzyl 浙江大洋生物科技集团股份有限公司 2025-01-28 CN disclosed
CN-116178100-A Dechlorination reduction method for 2-chloro-6-fluorotrichlorobenzyl 浙江大洋生物科技集团股份有限公司 2023-05-30 CN disclosed
CN-113861007-B Method for disposing 2-chloro-6 fluorobenzaldehyde distillation residues 浙江大洋生物科技集团股份有限公司 2023-04-25 CN disclosed
CN-113896653-A Synthesis and purification method of 2-chloro-6-fluorobenzonitrile 浙江大洋生物科技集团股份有限公司 2022-01-07 CN disclosed
CN-113861007-A Method for treating distillation residue of 2-chloro-6-fluorobenzaldehyde 浙江大洋生物科技集团股份有限公司 2021-12-31 CN disclosed
CN-1108193-C Novel catalyst for ethylene trimerization, its preparation process and application RES INST BEIJING YANSHAN PETRO (CN) 2003-05-14 CN disclosed
EP-0984919-B1 PROCESS FOR THE PREPARATION OF ARYLMALONATES BASF AG (DE) 2003-01-22 EP disclosed
EP-0599241-B2 Process for the preparation of aromatic aldehydes CLARIANT GMBH (DE) 2001-01-24 EP disclosed
EP-0599214-B2 Process for the continuous preparation of aromatic aldehydes CLARIANT GMBH (DE) 2001-01-24 EP disclosed
EP-0984919-A4 PROCESS FOR THE PREPARATION OF ARYLMALONATES AMERICAN CYANAMID CO (US) 2000-07-12 EP disclosed
WO-1998041496-A1 PROCESS FOR THE PREPARATION OF ARYLMALONATES AMERICAN CYANAMID COMPANY (US) 1998-09-24 WO disclosed
US-5756815-A DEHALOGENATION, CARBOXYLATION WITH MAGNESIUM AND DIALKYL CARBONATE OR AN ALKYL CHLOROFORMATE FOR INHIBITING BY-PRODUCT AMERICAN CYANAMID COMPANY (US) 1998-05-26 US disclosed
EP-0599214-B1 Process for the continuous preparation of aromatic aldehydes HOECHST AG (DE) 1997-08-13 EP disclosed
EP-0599241-B1 Process for the preparation of aromatic aldehydes HOECHST AG (DE) 1997-08-13 EP disclosed
US-5382694-A Process for the continuous production of aromatic aldehydes HOECHST AKTIENGESELLSCHAFT (DE) 1995-01-17 US disclosed
US-5347054-A Hydrolysis HOECHST AKTIENGESELLSCHAFT (DE) 1994-09-13 US disclosed
EP-0599241-A1 Process for the preparation of aromatic aldehydes HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-01 EP disclosed
EP-0599214-A1 Process for the continuous preparation of aromatic aldehydes HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-01 EP disclosed
US-5059731-A Selectively hydrogenating acetylenic and diolefinic hydrocarbons EUROPEANE DE RETRAITEMENT DE CATALYSEURS EURECAT (FR) 1991-10-22 US disclosed
US-4983559-A CATALYTIC REGENERATION EUROPEENE DE RETRAITEMENT DE CATALYSEURS EURECAT (FR) 1991-01-08 US disclosed