Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | ITGAL | P20701 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14955912 | 0.85 | CYP1A2 (0.43) | GAAALDH1A1TAAR1CYP1A2CYP2A6 | |
| SCHEMBL1397081 | 0.82 | ALDH1A1 (0.41) | GAAALDH1A1TAAR1CES2CES1 | |
| SCHEMBL18894118 | 0.82 | CES2 (0.43) | GAAALDH1A1TAAR1CES2CES1 | |
| SCHEMBL7181065 | 0.81 | GAA (0.44) | GAAALDH1A1TAAR1CES2CES1 | |
| SCHEMBL27743208 | 0.80 | CES2 (0.41) | GAAALDH1A1TAAR1CES2CES1 | |
| SCHEMBL4547923 | 0.79 | ALDH1A1 (0.42) | GAAALDH1A1TAAR1CES2CES1 | |
| SCHEMBL20256641 | 0.79 | TAAR1 (0.45) | GAAALDH1A1TAAR1CES2CES1 | |
| SCHEMBL11090617 | 0.77 | GAA (0.41) | GAAALDH1A1TAAR1CES2CES1 | |
| SCHEMBL23212814 | 0.76 | CES2 (0.41) | GAAALDH1A1TAAR1CES2CES1 | |
| SCHEMBL17553264 | 0.76 | ALDH1A1 (0.41) | GAAALDH1A1TAAR1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9439890-B2 | Triazolone compounds as mPGES-1 inhibitors | GLENMARK PHARMACEUTICALS S.A. (CH) | 2016-09-13 | — | — | US | disclosed |
| CN-105208859-A | Novel 4-aminopyridine and 6-aminopyrimidine carboxylates as herbicides | DOW AGROSCIENCES LLC | 2015-12-30 | — | — | CN | disclosed |
| US-20150283117-A1 | TRIAZOLONE COMPOUNDS AS mPGES-1 INHIBITORS | Ichnos Sciences SA (CH) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150283117-A1 | TRIAZOLONE COMPOUNDS AS mPGES-1 INHIBITORS | PTGES, PTGIS, PTGS1 | GAA 1416/4885ALDH1A1 157/4885TAAR1 285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.