Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.30 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7179230 | 0.97 | TRPA1 (0.30) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| Hydrochloric Acid SCHEMBL7185534 | 0.97 | TRPA1 (0.30) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| Hydrochloric Acid SCHEMBL7178384 | 0.97 | TRPA1 (0.30) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| Hydrochloric Acid SCHEMBL7179417 | 0.97 | TRPA1 (0.30) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| Hydrochloric Acid SCHEMBL7176628 | 0.97 | TRPA1 (0.30) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| Hydrochloric Acid SCHEMBL7176031 | 0.92 | GABRA1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL7181906 | 0.91 | GABRA1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL7175518 | 0.89 | GABRA1 (0.32) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| Hydrochloric Acid SCHEMBL7176247 | 0.89 | GABRA1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL7173893 | 0.89 | GABRA1 (0.35) | TRPA1LMNACHRM1SLC6A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |