Sugi Predict

Sugi Predict / Compounds / SCHEMBL7181232

SCHEMBL7181232

SCHEMBL7181232

CCOc1cccc(OCC)c1C(=O)c1ccccc1[P](=O)C(=O)c1c(Cl)cccc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HCRTR1 O43613 2/20 0.39
▸ L3MBTL1 Q9Y468 2/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ TSHR P16473 2/20 0.37
▸ RAB9A P51151 2/20 0.37
▸ LMNA P02545 2/20 0.37
▸ CNR2 P34972 2/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.37
▸ ELANE P08246 1/20 0.37
▸ GAA P10253 2/20 0.37
▸ MAPT P10636 2/20 0.37
▸ MAPK1 P28482 2/20 0.37
▸ MEN1 O00255 2/20 0.37
▸ KMT2A Q03164 2/20 0.37
▸ GLA P06280 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ USP2 O75604 1/20 0.37
▸ TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7182352 0.87 KCNK3 (0.44) HCRTR1L3MBTL1ALDH1A1TSHRRAB9A
SCHEMBL7189022 0.87 HCRTR1 (0.40) HCRTR1L3MBTL1ALDH1A1POLBRAB9A
SCHEMBL7175433 0.84 KCNK3 (0.39) HCRTR1L3MBTL1ALDH1A1RAB9ALMNA
SCHEMBL7182147 0.84 KCNK3 (0.48) HCRTR1L3MBTL1ALDH1A1RAB9ALMNA
SCHEMBL7732147 0.83 MAPT (0.44) HCRTR1ALDH1A1TSHRRAB9ALMNA
SCHEMBL7180911 0.83 CNR2 (0.40) L3MBTL1ALDH1A1LMNACNR2GAA
SCHEMBL7181297 0.82 MAPT (0.37) HCRTR1L3MBTL1RAB9ALMNACNR2
SCHEMBL7186470 0.81 RORC (0.42) L3MBTL1ALDH1A1RAB9ALMNASMN1; SMN2
SCHEMBL7182106 0.81 KMT2A (0.45) ALDH1A1POLBLMNASMN1; SMN2ELANE
SCHEMBL7188910 0.80 ALDH1A1 (0.44) ALDH1A1LMNACNR2GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 HCRTR1 1841/4885L3MBTL1 302/4885ALDH1A1 3416/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 HCRTR1 2117/4885L3MBTL1 126/4885ALDH1A1 3984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.